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Lentiviral delivery of the human wild-type tau protein mediates a slow and progressive neurodegenerative tau pathology in the rat brain.
Caillierez R, Bégard S, Lécolle K, Deramecourt V, Zommer N, Dujardin S, Loyens A, Dufour N, Aurégan G, Winderickx J, Hantraye P, Déglon N, Buée L, Colin M. Caillierez R, et al. Among authors: dujardin s. Mol Ther. 2013 Jul;21(7):1358-68. doi: 10.1038/mt.2013.66. Epub 2013 Apr 23. Mol Ther. 2013. PMID: 23609018 Free PMC article.
Ectosomes: a new mechanism for non-exosomal secretion of tau protein.
Dujardin S, Bégard S, Caillierez R, Lachaud C, Delattre L, Carrier S, Loyens A, Galas MC, Bousset L, Melki R, Aurégan G, Hantraye P, Brouillet E, Buée L, Colin M. Dujardin S, et al. PLoS One. 2014 Jun 27;9(6):e100760. doi: 10.1371/journal.pone.0100760. eCollection 2014. PLoS One. 2014. PMID: 24971751 Free PMC article.
What is the evidence that tau pathology spreads through prion-like propagation?
Mudher A, Colin M, Dujardin S, Medina M, Dewachter I, Alavi Naini SM, Mandelkow EM, Mandelkow E, Buée L, Goedert M, Brion JP. Mudher A, et al. Among authors: dujardin s. Acta Neuropathol Commun. 2017 Dec 19;5(1):99. doi: 10.1186/s40478-017-0488-7. Acta Neuropathol Commun. 2017. PMID: 29258615 Free PMC article. Review.
Different tau species lead to heterogeneous tau pathology propagation and misfolding.
Dujardin S, Bégard S, Caillierez R, Lachaud C, Carrier S, Lieger S, Gonzalez JA, Deramecourt V, Déglon N, Maurage CA, Frosch MP, Hyman BT, Colin M, Buée L. Dujardin S, et al. Acta Neuropathol Commun. 2018 Nov 29;6(1):132. doi: 10.1186/s40478-018-0637-7. Acta Neuropathol Commun. 2018. PMID: 30497516 Free PMC article.
65 results