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A MYC-GCN2-eIF2α negative feedback loop limits protein synthesis to prevent MYC-dependent apoptosis in colorectal cancer.
Schmidt S, Gay D, Uthe FW, Denk S, Paauwe M, Matthes N, Diefenbacher ME, Bryson S, Warrander FC, Erhard F, Ade CP, Baluapuri A, Walz S, Jackstadt R, Ford C, Vlachogiannis G, Valeri N, Otto C, Schülein-Völk C, Maurus K, Schmitz W, Knight JRP, Wolf E, Strathdee D, Schulze A, Germer CT, Rosenwald A, Sansom OJ, Eilers M, Wiegering A. Schmidt S, et al. Among authors: eilers m. Nat Cell Biol. 2019 Nov;21(11):1413-1424. doi: 10.1038/s41556-019-0408-0. Epub 2019 Nov 4. Nat Cell Biol. 2019. PMID: 31685988 Free PMC article.
Repression of p15INK4b expression by Myc through association with Miz-1.
Staller P, Peukert K, Kiermaier A, Seoane J, Lukas J, Karsunky H, Möröy T, Bartek J, Massagué J, Hänel F, Eilers M. Staller P, et al. Among authors: eilers m. Nat Cell Biol. 2001 Apr;3(4):392-9. doi: 10.1038/35070076. Nat Cell Biol. 2001. PMID: 11283613
Transcriptional repression by Myc.
Wanzel M, Herold S, Eilers M. Wanzel M, et al. Among authors: eilers m. Trends Cell Biol. 2003 Mar;13(3):146-50. doi: 10.1016/s0962-8924(03)00003-5. Trends Cell Biol. 2003. PMID: 12628347 Review.
The ubiquitin-specific protease USP28 is required for MYC stability.
Popov N, Wanzel M, Madiredjo M, Zhang D, Beijersbergen R, Bernards R, Moll R, Elledge SJ, Eilers M. Popov N, et al. Among authors: eilers m. Nat Cell Biol. 2007 Jul;9(7):765-74. doi: 10.1038/ncb1601. Epub 2007 Jun 10. Nat Cell Biol. 2007. PMID: 17558397
Stabilization of N-Myc is a critical function of Aurora A in human neuroblastoma.
Otto T, Horn S, Brockmann M, Eilers U, Schüttrumpf L, Popov N, Kenney AM, Schulte JH, Beijersbergen R, Christiansen H, Berwanger B, Eilers M. Otto T, et al. Among authors: eilers u, eilers m. Cancer Cell. 2009 Jan 6;15(1):67-78. doi: 10.1016/j.ccr.2008.12.005. Cancer Cell. 2009. PMID: 19111882 Free article.
300 results