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Moving towards a new era of genomics in the neuronal ceroid lipofuscinoses.
Biochim Biophys Acta Mol Basis Dis. 2020 Sep 1;1866(9):165571. doi: 10.1016/j.bbadis.2019.165571. Epub 2019 Oct 31.
Biochim Biophys Acta Mol Basis Dis. 2020.
PMID: 31678159
Free article.
Review.
Human iPSC models of neuronal ceroid lipofuscinosis capture distinct effects of TPP1 and CLN3 mutations on the endocytic pathway.
Lojewski X, Staropoli JF, Biswas-Legrand S, Simas AM, Haliw L, Selig MK, Coppel SH, Goss KA, Petcherski A, Chandrachud U, Sheridan SD, Lucente D, Sims KB, Gusella JF, Sondhi D, Crystal RG, Reinhardt P, Sterneckert J, Schöler H, Haggarty SJ, Storch A, Hermann A, Cotman SL.
Lojewski X, et al. Among authors: chandrachud u.
Hum Mol Genet. 2014 Apr 15;23(8):2005-22. doi: 10.1093/hmg/ddt596. Epub 2013 Nov 23.
Hum Mol Genet. 2014.
PMID: 24271013
Free PMC article.
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An Autophagy Modifier Screen Identifies Small Molecules Capable of Reducing Autophagosome Accumulation in a Model of CLN3-Mediated Neurodegeneration.
Petcherski A, Chandrachud U, Butz ES, Klein MC, Zhao WN, Reis SA, Haggarty SJ, Ruonala MO, Cotman SL.
Petcherski A, et al. Among authors: chandrachud u.
Cells. 2019 Nov 27;8(12):1531. doi: 10.3390/cells8121531.
Cells. 2019.
PMID: 31783699
Free PMC article.
Item in Clipboard
Unbiased Cell-based Screening in a Neuronal Cell Model of Batten Disease Highlights an Interaction between Ca2+ Homeostasis, Autophagy, and CLN3 Protein Function.
Chandrachud U, Walker MW, Simas AM, Heetveld S, Petcherski A, Klein M, Oh H, Wolf P, Zhao WN, Norton S, Haggarty SJ, Lloyd-Evans E, Cotman SL.
Chandrachud U, et al.
J Biol Chem. 2015 Jun 5;290(23):14361-80. doi: 10.1074/jbc.M114.621706. Epub 2015 Apr 15.
J Biol Chem. 2015.
PMID: 25878248
Free PMC article.
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The CLN3 gene and protein: What we know.
Mirza M, Vainshtein A, DiRonza A, Chandrachud U, Haslett LJ, Palmieri M, Storch S, Groh J, Dobzinski N, Napolitano G, Schmidtke C, Kerkovich DM.
Mirza M, et al. Among authors: chandrachud u.
Mol Genet Genomic Med. 2019 Dec;7(12):e859. doi: 10.1002/mgg3.859. Epub 2019 Sep 30.
Mol Genet Genomic Med. 2019.
PMID: 31568712
Free PMC article.
Review.
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Scintillation proximity assay for total p53 protein as an alternative to ELISA.
Oberlander S, Xie T, Chandrachud U, Gal S.
Oberlander S, et al. Among authors: chandrachud u.
J Immunol Methods. 2010 Aug 31;360(1-2):173-7. doi: 10.1016/j.jim.2010.06.018. Epub 2010 Jun 30.
J Immunol Methods. 2010.
PMID: 20600074
Free PMC article.
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Three assays show differences in binding of wild-type and mutant p53 to unique gene sequences.
Chandrachud U, Gal S.
Chandrachud U, et al.
Technol Cancer Res Treat. 2009 Dec;8(6):445-53. doi: 10.1177/153303460900800606.
Technol Cancer Res Treat. 2009.
PMID: 19925028
Free PMC article.
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Assembly-disassembly of DNAs and gold nanoparticles: a strategy of intervention based on oligonucleotides and restriction enzymes.
Lim II, Chandrachud U, Wang L, Gal S, Zhong CJ.
Lim II, et al. Among authors: chandrachud u.
Anal Chem. 2008 Aug 1;80(15):6038-44. doi: 10.1021/ac800813a. Epub 2008 Jul 9.
Anal Chem. 2008.
PMID: 18613651
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