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Excess mucus viscosity and airway dehydration impact COPD airway clearance.
Lin VY, Kaza N, Birket SE, Kim H, Edwards LJ, LaFontaine J, Liu L, Mazur M, Byzek SA, Hanes J, Tearney GJ, Raju SV, Rowe SM. Lin VY, et al. Among authors: tearney gj. Eur Respir J. 2020 Jan 30;55(1):1900419. doi: 10.1183/13993003.00419-2019. Print 2020 Jan. Eur Respir J. 2020. PMID: 31672759 Free PMC article.
An autoregulatory mechanism governing mucociliary transport is sensitive to mucus load.
Liu L, Shastry S, Byan-Parker S, Houser G, K Chu K, Birket SE, Fernandez CM, Gardecki JA, Grizzle WE, Wilsterman EJ, Sorscher EJ, Rowe SM, Tearney GJ. Liu L, et al. Among authors: tearney gj. Am J Respir Cell Mol Biol. 2014 Oct;51(4):485-93. doi: 10.1165/rcmb.2013-0499MA. Am J Respir Cell Mol Biol. 2014. PMID: 24937762 Free PMC article.
A functional anatomic defect of the cystic fibrosis airway.
Birket SE, Chu KK, Liu L, Houser GH, Diephuis BJ, Wilsterman EJ, Dierksen G, Mazur M, Shastry S, Li Y, Watson JD, Smith AT, Schuster BS, Hanes J, Grizzle WE, Sorscher EJ, Tearney GJ, Rowe SM. Birket SE, et al. Among authors: tearney gj. Am J Respir Crit Care Med. 2014 Aug 15;190(4):421-32. doi: 10.1164/rccm.201404-0670OC. Am J Respir Crit Care Med. 2014. PMID: 25029666 Free PMC article.
Defective innate immunity and hyperinflammation in newborn cystic fibrosis transmembrane conductance regulator-knockout ferret lungs.
Keiser NW, Birket SE, Evans IA, Tyler SR, Crooke AK, Sun X, Zhou W, Nellis JR, Stroebele EK, Chu KK, Tearney GJ, Stevens MJ, Harris JK, Rowe SM, Engelhardt JF. Keiser NW, et al. Among authors: tearney gj. Am J Respir Cell Mol Biol. 2015 Jun;52(6):683-94. doi: 10.1165/rcmb.2014-0250OC. Am J Respir Cell Mol Biol. 2015. PMID: 25317669 Free PMC article.
Combination therapy with cystic fibrosis transmembrane conductance regulator modulators augment the airway functional microanatomy.
Birket SE, Chu KK, Houser GH, Liu L, Fernandez CM, Solomon GM, Lin V, Shastry S, Mazur M, Sloane PA, Hanes J, Grizzle WE, Sorscher EJ, Tearney GJ, Rowe SM. Birket SE, et al. Among authors: tearney gj. Am J Physiol Lung Cell Mol Physiol. 2016 May 15;310(10):L928-39. doi: 10.1152/ajplung.00395.2015. Epub 2016 Mar 11. Am J Physiol Lung Cell Mol Physiol. 2016. PMID: 26968770 Free PMC article.
334 results