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STIM1 and ORAI1 mutations leading to tubular aggregate myopathies are sensitive to the Store-operated Ca2+-entry modulators CIC-37 and CIC-39.
Riva B, Pessolano E, Quaglia E, Cordero-Sanchez C, Bhela IP, Topf A, Serafini M, Cox D, Harris E, Garibaldi M, Barresi R, Pirali T, Genazzani AA. Riva B, et al. Among authors: cordero sanchez c. Cell Calcium. 2022 Jul;105:102605. doi: 10.1016/j.ceca.2022.102605. Epub 2022 May 18. Cell Calcium. 2022. PMID: 35636153 Free article.
CIC-39Na reverses the thrombocytopenia that characterizes tubular aggregate myopathy.
Cordero-Sanchez C, Pessolano E, Riva B, Vismara M, Trivigno SMG, Clemente N, Aprile S, Ruffinatti FA, Portararo P, Filigheddu N, Zaggia I, Bhela IP, Serafini M, Pirali T, Colombo MP, Torti M, Sangaletti S, Bertoni A, Genazzani AA. Cordero-Sanchez C, et al. Blood Adv. 2022 Aug 9;6(15):4471-4484. doi: 10.1182/bloodadvances.2021006378. Blood Adv. 2022. PMID: 35696753 Free PMC article.
Store-Operated Calcium Entry as a Therapeutic Target in Acute Pancreatitis: Discovery and Development of Drug-Like SOCE Inhibitors.
Serafini M, Cordero-Sanchez C, Di Paola R, Bhela IP, Aprile S, Purghè B, Fusco R, Cuzzocrea S, Genazzani AA, Riva B, Pirali T. Serafini M, et al. Among authors: cordero sanchez c. J Med Chem. 2020 Dec 10;63(23):14761-14779. doi: 10.1021/acs.jmedchem.0c01305. Epub 2020 Nov 30. J Med Chem. 2020. PMID: 33253576 Free PMC article.
Oxaliplatin induces pH acidification in dorsal root ganglia neurons.
Riva B, Dionisi M, Potenzieri A, Chiorazzi A, Cordero-Sanchez C, Rigolio R, Carozzi VA, Lim D, Cavaletti G, Marmiroli P, Distasi C, Genazzani AA. Riva B, et al. Among authors: cordero sanchez c. Sci Rep. 2018 Oct 10;8(1):15084. doi: 10.1038/s41598-018-33508-6. Sci Rep. 2018. PMID: 30305703 Free PMC article.
Pyrtriazoles, a Novel Class of Store-Operated Calcium Entry Modulators: Discovery, Biological Profiling, and in Vivo Proof-of-Concept Efficacy in Acute Pancreatitis.
Riva B, Griglio A, Serafini M, Cordero-Sanchez C, Aprile S, Di Paola R, Gugliandolo E, Alansary D, Biocotino I, Lim D, Grosa G, Galli U, Niemeyer B, Sorba G, Canonico PL, Cuzzocrea S, Genazzani AA, Pirali T. Riva B, et al. Among authors: cordero sanchez c. J Med Chem. 2018 Nov 8;61(21):9756-9783. doi: 10.1021/acs.jmedchem.8b01512. Epub 2018 Oct 30. J Med Chem. 2018. PMID: 30347159
Cellular and animal models for the investigation of β-thalassemia.
Nai A, Cordero-Sanchez C, Tanzi E, Pagani A, Silvestri L, Di Modica SM. Nai A, et al. Among authors: cordero sanchez c. Blood Cells Mol Dis. 2024 Jan;104:102761. doi: 10.1016/j.bcmd.2023.102761. Epub 2023 May 30. Blood Cells Mol Dis. 2024. PMID: 37271682 Review.
A single approach to targeting transferrin receptor 2 corrects iron and erythropoietic defects in murine models of anemia of inflammation and chronic kidney disease.
Olivari V, Di Modica SM, Lidonnici MR, Aghajan M, Cordero-Sanchez C, Tanzi E, Pettinato M, Pagani A, Tiboni F, Silvestri L, Guo S, Ferrari G, Nai A. Olivari V, et al. Among authors: cordero sanchez c. Kidney Int. 2023 Jul;104(1):61-73. doi: 10.1016/j.kint.2023.03.012. Epub 2023 Mar 27. Kidney Int. 2023. PMID: 36990212