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Page 1
Variation of PEAR1 DNA methylation influences platelet and leukocyte function.
Izzi B, Gianfagna F, Yang WY, Cludts K, De Curtis A, Verhamme P, Di Castelnuovo A, Cerletti C, Donati MB, de Gaetano G, Staessen JA, Hoylaerts MF, Iacoviello L; Moli-family Investigators. Izzi B, et al. Among authors: hoylaerts mf. Clin Epigenetics. 2019 Oct 29;11(1):151. doi: 10.1186/s13148-019-0744-8. Clin Epigenetics. 2019. PMID: 31665082 Free PMC article.
Absence of Pear1 does not affect murine platelet function in vivo.
Criel M, Izzi B, Vandenbriele C, Liesenborghs L, Van Kerckhoven S, Lox M, Cludts K, Jones EA, Vanassche T, Verhamme P, Hoylaerts M. Criel M, et al. Thromb Res. 2016 Oct;146:76-83. doi: 10.1016/j.thromres.2016.08.026. Epub 2016 Aug 26. Thromb Res. 2016. PMID: 27614188
Allele-specific DNA methylation reinforces PEAR1 enhancer activity.
Izzi B, Pistoni M, Cludts K, Akkor P, Lambrechts D, Verfaillie C, Verhamme P, Freson K, Hoylaerts MF. Izzi B, et al. Among authors: hoylaerts mf. Blood. 2016 Aug 18;128(7):1003-12. doi: 10.1182/blood-2015-11-682153. Epub 2016 Jun 16. Blood. 2016. PMID: 27313330 Free article.
Platelet Distribution Width Is Associated with P-Selectin Dependent Platelet Function: Results from the Moli-Family Cohort Study.
Izzi B, Gialluisi A, Gianfagna F, Orlandi S, De Curtis A, Magnacca S, Costanzo S, Di Castelnuovo A, Donati MB, de Gaetano G, Hoylaerts MF, Cerletti C, Iacoviello L, On Behalf Of The Moli-Family Study Investigators. Izzi B, et al. Among authors: hoylaerts mf. Cells. 2021 Oct 13;10(10):2737. doi: 10.3390/cells10102737. Cells. 2021. PMID: 34685717 Free PMC article.
ZBTB12 DNA methylation is associated with coagulation- and inflammation-related blood cell parameters: findings from the Moli-family cohort.
Noro F, Gianfagna F, Gialluisi A, De Curtis A, Di Castelnuovo A, Napoleone E, Cerletti C, Donati MB, de Gaetano G, Hoylaerts MF, Iacoviello L, Izzi B; Moli-family study Investigators. Noro F, et al. Among authors: hoylaerts mf. Clin Epigenetics. 2019 May 10;11(1):74. doi: 10.1186/s13148-019-0665-6. Clin Epigenetics. 2019. PMID: 31077224 Free PMC article.
Association of colorectal cancer with genetic and epigenetic variation in PEAR1-A population-based cohort study.
Yang WY, Izzi B, Bress AP, Thijs L, Citterio L, Wei FF, Salvi E, Delli Carpini S, Manunta P, Cusi D, Hoylaerts MF, Luttun A, Verhamme P, Hardikar S, Nawrot TS, Staessen JA, Zhang ZY. Yang WY, et al. Among authors: hoylaerts mf. PLoS One. 2022 Apr 7;17(4):e0266481. doi: 10.1371/journal.pone.0266481. eCollection 2022. PLoS One. 2022. PMID: 35390065 Free PMC article.
A novel mechanism of sustained platelet αIIbβ3 activation via PEAR1.
Kauskot A, Di Michele M, Loyen S, Freson K, Verhamme P, Hoylaerts MF. Kauskot A, et al. Among authors: hoylaerts mf. Blood. 2012 Apr 26;119(17):4056-65. doi: 10.1182/blood-2011-11-392787. Epub 2012 Feb 27. Blood. 2012. PMID: 22371881 Free article.
Dextran sulfate triggers platelet aggregation via direct activation of PEAR1.
Vandenbriele C, Sun Y, Criel M, Cludts K, Van Kerckhoven S, Izzi B, Vanassche T, Verhamme P, Hoylaerts MF. Vandenbriele C, et al. Among authors: hoylaerts mf. Platelets. 2016 Jun;27(4):365-72. doi: 10.3109/09537104.2015.1111321. Epub 2015 Nov 30. Platelets. 2016. PMID: 26619766
297 results