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PPM1H phosphatase counteracts LRRK2 signaling by selectively dephosphorylating Rab proteins.
Elife. 2019 Oct 30;8:e50416. doi: 10.7554/eLife.50416.
Elife. 2019.
PMID: 31663853
Free PMC article.
Genome-wide interrogation of extracellular vesicle biology using barcoded miRNAs.
Lu A, Wawro P, Morgens DW, Portela F, Bassik MC, Pfeffer SR.
Lu A, et al.
Elife. 2018 Dec 17;7:e41460. doi: 10.7554/eLife.41460.
Elife. 2018.
PMID: 30556811
Free PMC article.
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Membrane association but not identity is required for LRRK2 activation and phosphorylation of Rab GTPases.
Gomez RC, Wawro P, Lis P, Alessi DR, Pfeffer SR.
Gomez RC, et al.
J Cell Biol. 2019 Dec 2;218(12):4157-4170. doi: 10.1083/jcb.201902184. Epub 2019 Oct 17.
J Cell Biol. 2019.
PMID: 31624137
Free PMC article.
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Pathogenic LRRK2 regulates ciliation probability upstream of tau tubulin kinase 2 via Rab10 and RILPL1 proteins.
Sobu Y, Wawro PS, Dhekne HS, Yeshaw WM, Pfeffer SR.
Sobu Y, et al. Among authors: wawro ps.
Proc Natl Acad Sci U S A. 2021 Mar 9;118(10):e2005894118. doi: 10.1073/pnas.2005894118.
Proc Natl Acad Sci U S A. 2021.
PMID: 33653948
Free PMC article.
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Localization of PPM1H phosphatase tunes Parkinson's disease-linked LRRK2 kinase-mediated Rab GTPase phosphorylation and ciliogenesis.
Yeshaw WM, Adhikari A, Chiang CY, Dhekne HS, Wawro PS, Pfeffer SR.
Yeshaw WM, et al. Among authors: wawro ps.
Proc Natl Acad Sci U S A. 2023 Oct 31;120(44):e2315171120. doi: 10.1073/pnas.2315171120. Epub 2023 Oct 27.
Proc Natl Acad Sci U S A. 2023.
PMID: 37889931
Free PMC article.
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Comprehensive knockout analysis of the Rab family GTPases in epithelial cells.
Homma Y, Kinoshita R, Kuchitsu Y, Wawro PS, Marubashi S, Oguchi ME, Ishida M, Fujita N, Fukuda M.
Homma Y, et al. Among authors: wawro ps.
J Cell Biol. 2019 Jun 3;218(6):2035-2050. doi: 10.1083/jcb.201810134. Epub 2019 May 9.
J Cell Biol. 2019.
PMID: 31072826
Free PMC article.
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