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Lactate-mediated epigenetic reprogramming regulates formation of human pancreatic cancer-associated fibroblasts.
Bhagat TD, Von Ahrens D, Dawlaty M, Zou Y, Baddour J, Achreja A, Zhao H, Yang L, Patel B, Kwak C, Choudhary GS, Gordon-Mitchell S, Aluri S, Bhattacharyya S, Sahu S, Bhagat P, Yu Y, Bartenstein M, Giricz O, Suzuki M, Sohal D, Gupta S, Guerrero PA, Batra S, Goggins M, Steidl U, Greally J, Agarwal B, Pradhan K, Banerjee D, Nagrath D, Maitra A, Verma A. Bhagat TD, et al. Among authors: zhao h. Elife. 2019 Nov 1;8:e50663. doi: 10.7554/eLife.50663. Elife. 2019. PMID: 31663852 Free PMC article.
Metabolic shifts toward glutamine regulate tumor growth, invasion and bioenergetics in ovarian cancer.
Yang L, Moss T, Mangala LS, Marini J, Zhao H, Wahlig S, Armaiz-Pena G, Jiang D, Achreja A, Win J, Roopaimoole R, Rodriguez-Aguayo C, Mercado-Uribe I, Lopez-Berestein G, Liu J, Tsukamoto T, Sood AK, Ram PT, Nagrath D. Yang L, et al. Among authors: zhao h. Mol Syst Biol. 2014 May 5;10(5):728. doi: 10.1002/msb.20134892. Mol Syst Biol. 2014. PMID: 24799285 Free PMC article.
The key role of extracellular vesicles in the metastatic process.
Zhao H, Achreja A, Iessi E, Logozzi M, Mizzoni D, Di Raimo R, Nagrath D, Fais S. Zhao H, et al. Biochim Biophys Acta Rev Cancer. 2018 Jan;1869(1):64-77. doi: 10.1016/j.bbcan.2017.11.005. Epub 2017 Nov 24. Biochim Biophys Acta Rev Cancer. 2018. PMID: 29175553 Free PMC article. Review.
ITLN1 modulates invasive potential and metabolic reprogramming of ovarian cancer cells in omental microenvironment.
Au-Yeung CL, Yeung TL, Achreja A, Zhao H, Yip KP, Kwan SY, Onstad M, Sheng J, Zhu Y, Baluya DL, Co NN, Rynne-Vidal A, Schmandt R, Anderson ML, Lu KH, Wong STC, Nagrath D, Mok SC. Au-Yeung CL, et al. Among authors: zhao h. Nat Commun. 2020 Jul 15;11(1):3546. doi: 10.1038/s41467-020-17383-2. Nat Commun. 2020. PMID: 32669559 Free PMC article.
Myeloid-derived itaconate suppresses cytotoxic CD8+ T cells and promotes tumour growth.
Zhao H, Teng D, Yang L, Xu X, Chen J, Jiang T, Feng AY, Zhang Y, Frederick DT, Gu L, Cai L, Asara JM, Pasca di Magliano M, Boland GM, Flaherty KT, Swanson KD, Liu D, Rabinowitz JD, Zheng B. Zhao H, et al. Nat Metab. 2022 Dec;4(12):1660-1673. doi: 10.1038/s42255-022-00676-9. Epub 2022 Nov 14. Nat Metab. 2022. PMID: 36376563 Free PMC article.
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