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Multiple Synthetic Routes to the Mini-Protein Omomyc and Coiled-Coil Domain Truncations.
Brown ZZ, Mapelli C, Farasat I, Shoultz AV, Johnson SA, Orvieto F, Santoprete A, Bianchi E, McCracken AB, Chen K, Zhu X, Demma MJ, Lacey BM, Canada KA, Garbaccio RM, O'Neil J, Walji A. Brown ZZ, et al. Among authors: mapelli c. J Org Chem. 2020 Feb 7;85(3):1466-1475. doi: 10.1021/acs.joc.9b02467. Epub 2019 Nov 25. J Org Chem. 2020. PMID: 31660743
Omomyc Reveals New Mechanisms To Inhibit the MYC Oncogene.
Demma MJ, Mapelli C, Sun A, Bodea S, Ruprecht B, Javaid S, Wiswell D, Muise E, Chen S, Zelina J, Orvieto F, Santoprete A, Altezza S, Tucci F, Escandon E, Hall B, Ray K, Walji A, O'Neil J. Demma MJ, et al. Among authors: mapelli c. Mol Cell Biol. 2019 Oct 28;39(22):e00248-19. doi: 10.1128/MCB.00248-19. Print 2019 Nov 15. Mol Cell Biol. 2019. PMID: 31501275 Free PMC article.
Process Development of a Macrocyclic Peptide Inhibitor of PD-L1.
Mukherjee S, Rogers A, Creech G, Hang C, Ramirez A, Dummeldinger M, Brueggemeier S, Mapelli C, Zaretsky S, Huang M, Black R, Peddicord MB, Cuniere N, Kempson J, Pawluczyk J, Allen M, Parsons R, Sfouggatakis C. Mukherjee S, et al. Among authors: mapelli c. J Org Chem. 2024 May 17;89(10):6651-6663. doi: 10.1021/acs.joc.4c00430. Epub 2024 Apr 25. J Org Chem. 2024. PMID: 38663026
NEMO binding domain of IKK-2 encompasses amino acids 735-745.
Strnad J, McDonnell PA, Riexinger DJ, Mapelli C, Cheng L, Gray H, Ryseck RP, Burke JR. Strnad J, et al. Among authors: mapelli c. J Mol Recognit. 2006 May-Jun;19(3):227-33. doi: 10.1002/jmr.766. J Mol Recognit. 2006. PMID: 16583354
Eleven amino acid glucagon-like peptide-1 receptor agonists with antidiabetic activity.
Mapelli C, Natarajan SI, Meyer JP, Bastos MM, Bernatowicz MS, Lee VG, Pluscec J, Riexinger DJ, Sieber-McMaster ES, Constantine KL, Smith-Monroy CA, Golla R, Ma Z, Longhi DA, Shi D, Xin L, Taylor JR, Koplowitz B, Chi CL, Khanna A, Robinson GW, Seethala R, Antal-Zimanyi IA, Stoffel RH, Han S, Whaley JM, Huang CS, Krupinski J, Ewing WR. Mapelli C, et al. J Med Chem. 2009 Dec 10;52(23):7788-99. doi: 10.1021/jm900752a. J Med Chem. 2009. PMID: 19702274
Synthesis of a stable isotopically labeled universal surrogate peptide for use as an internal standard in LC-MS/MS bioanalysis of human IgG and Fc-fusion protein drug candidates.
Voronin K, Allentoff AJ, Bonacorsi SJ Jr, Mapelli C, Gong SX, Lee V, Riexinger D, Sanghvi N, Jiang H, Zeng J. Voronin K, et al. Among authors: mapelli c. J Labelled Comp Radiopharm. 2014 Jul;57(9):579-83. doi: 10.1002/jlcr.3218. Epub 2014 Aug 4. J Labelled Comp Radiopharm. 2014. PMID: 25089024
88 results