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Synthetic lethality by targeting the RUVBL1/2-TTT complex in mTORC1-hyperactive cancer cells.
Shin SH, Lee JS, Zhang JM, Choi S, Boskovic ZV, Zhao R, Song M, Wang R, Tian J, Lee MH, Kim JH, Jeong M, Lee JH, Petukhov M, Lee SW, Kim SG, Zou L, Byun S. Shin SH, et al. Among authors: lee sw, lee js, lee mh, lee jh. Sci Adv. 2020 Jul 31;6(31):eaay9131. doi: 10.1126/sciadv.aay9131. eCollection 2020 Jul. Sci Adv. 2020. PMID: 32789167 Free PMC article.
8-Shogaol inhibits rheumatoid arthritis through targeting TAK1.
Jo S, Samarpita S, Lee JS, Lee YJ, Son JE, Jeong M, Kim JH, Hong S, Yoo SA, Kim WU, Rasool M, Byun S. Jo S, et al. Among authors: lee js, lee yj. Pharmacol Res. 2022 Apr;178:106176. doi: 10.1016/j.phrs.2022.106176. Epub 2022 Mar 10. Pharmacol Res. 2022. PMID: 35283302
The N-terminal cysteine is a dual sensor of oxygen and oxidative stress.
Heo AJ, Kim SB, Ji CH, Han D, Lee SJ, Lee SH, Lee MJ, Lee JS, Ciechanover A, Kim BY, Kwon YT. Heo AJ, et al. Among authors: lee sh, lee sj, lee js, lee mj. Proc Natl Acad Sci U S A. 2021 Dec 14;118(50):e2107993118. doi: 10.1073/pnas.2107993118. Proc Natl Acad Sci U S A. 2021. PMID: 34893540 Free PMC article.
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