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IGSF1 Deficiency Results in Human and Murine Somatotrope Neurosecretory Hyperfunction.
Joustra SD, Roelfsema F, van Trotsenburg ASP, Schneider HJ, Kosilek RP, Kroon HM, Logan JG, Butterfield NC, Zhou X, Toufaily C, Bak B, Turgeon MO, Brûlé E, Steyn FJ, Gurnell M, Koulouri O, Le Tissier P, Fontanaud P, Duncan Bassett JH, Williams GR, Oostdijk W, Wit JM, Pereira AM, Biermasz NR, Bernard DJ, Schoenmakers N. Joustra SD, et al. Among authors: gurnell m. J Clin Endocrinol Metab. 2020 Mar 1;105(3):e70-84. doi: 10.1210/clinem/dgz093. J Clin Endocrinol Metab. 2020. PMID: 31650157 Free PMC article.
Elevated plasma adiponectin in humans with genetically defective insulin receptors.
Semple RK, Soos MA, Luan J, Mitchell CS, Wilson JC, Gurnell M, Cochran EK, Gorden P, Chatterjee VK, Wareham NJ, O'Rahilly S. Semple RK, et al. Among authors: gurnell m. J Clin Endocrinol Metab. 2006 Aug;91(8):3219-23. doi: 10.1210/jc.2006-0166. Epub 2006 May 16. J Clin Endocrinol Metab. 2006. PMID: 16705075
Mutations in the selenocysteine insertion sequence-binding protein 2 gene lead to a multisystem selenoprotein deficiency disorder in humans.
Schoenmakers E, Agostini M, Mitchell C, Schoenmakers N, Papp L, Rajanayagam O, Padidela R, Ceron-Gutierrez L, Doffinger R, Prevosto C, Luan J, Montano S, Lu J, Castanet M, Clemons N, Groeneveld M, Castets P, Karbaschi M, Aitken S, Dixon A, Williams J, Campi I, Blount M, Burton H, Muntoni F, O'Donovan D, Dean A, Warren A, Brierley C, Baguley D, Guicheney P, Fitzgerald R, Coles A, Gaston H, Todd P, Holmgren A, Khanna KK, Cooke M, Semple R, Halsall D, Wareham N, Schwabe J, Grasso L, Beck-Peccoz P, Ogunko A, Dattani M, Gurnell M, Chatterjee K. Schoenmakers E, et al. Among authors: gurnell m. J Clin Invest. 2010 Dec;120(12):4220-35. doi: 10.1172/JCI43653. Epub 2010 Nov 15. J Clin Invest. 2010. PMID: 21084748 Free PMC article.
Increased prevalence of gallbladder polyps in acromegaly.
Annamalai AK, Gayton EL, Webb A, Halsall DJ, Rice C, Ibram F, Chaudhry AN, Simpson HL, Berman L, Gurnell M. Annamalai AK, et al. Among authors: gurnell m. J Clin Endocrinol Metab. 2011 Jul;96(7):E1120-5. doi: 10.1210/jc.2010-2669. Epub 2011 May 4. J Clin Endocrinol Metab. 2011. PMID: 21543430
A mutation in the thyroid hormone receptor alpha gene.
Bochukova E, Schoenmakers N, Agostini M, Schoenmakers E, Rajanayagam O, Keogh JM, Henning E, Reinemund J, Gevers E, Sarri M, Downes K, Offiah A, Albanese A, Halsall D, Schwabe JW, Bain M, Lindley K, Muntoni F, Vargha-Khadem F, Dattani M, Farooqi IS, Gurnell M, Chatterjee K. Bochukova E, et al. Among authors: gurnell m. N Engl J Med. 2012 Jan 19;366(3):243-9. doi: 10.1056/NEJMoa1110296. Epub 2011 Dec 14. N Engl J Med. 2012. PMID: 22168587 Free article.
A comprehensive study of clinical, biochemical, radiological, vascular, cardiac, and sleep parameters in an unselected cohort of patients with acromegaly undergoing presurgical somatostatin receptor ligand therapy.
Annamalai AK, Webb A, Kandasamy N, Elkhawad M, Moir S, Khan F, Maki-Petaja K, Gayton EL, Strey CH, O'Toole S, Ariyaratnam S, Halsall DJ, Chaudhry AN, Berman L, Scoffings DJ, Antoun NM, Dutka DP, Wilkinson IB, Shneerson JM, Pickard JD, Simpson HL, Gurnell M. Annamalai AK, et al. Among authors: gurnell m. J Clin Endocrinol Metab. 2013 Mar;98(3):1040-50. doi: 10.1210/jc.2012-3072. Epub 2013 Feb 7. J Clin Endocrinol Metab. 2013. PMID: 23393175 Clinical Trial.
How to interpret thyroid function tests.
Koulouri O, Gurnell M. Koulouri O, et al. Among authors: gurnell m. Clin Med (Lond). 2013 Jun;13(3):282-6. doi: 10.7861/clinmedicine.13-3-282. Clin Med (Lond). 2013. PMID: 23760704 Free PMC article. No abstract available.
178 results