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Targeting the Somatostatin Receptor 2 with the Miniaturized Drug Conjugate, PEN-221: A Potent and Novel Therapeutic for the Treatment of Small Cell Lung Cancer.
Whalen KA, White BH, Quinn JM, Kriksciukaite K, Alargova R, Au Yeung TP, Bazinet P, Brockman A, DuPont MM, Oller H, Gifford J, Lemelin CA, Lim Soo P, Perino S, Moreau B, Sharma G, Shinde R, Sweryda-Krawiec B, Bilodeau MT, Wooster R. Whalen KA, et al. Among authors: perino s. Mol Cancer Ther. 2019 Nov;18(11):1926-1936. doi: 10.1158/1535-7163.MCT-19-0022. Mol Cancer Ther. 2019. PMID: 31649014
Novel Miniaturized Drug Conjugate Leverages HSP90-driven Tumor Accumulation to Overcome PI3K Inhibitor Delivery Challenges to Solid Tumors.
Perino S, Moreau B, Freda J, Cirello A, White BH, Quinn JM, Kriksciukaite K, Someshwar A, Romagnoli J, Robinson M, Movassaghian S, Cipriani T, Wooster R, Bilodeau MT, Whalen KA. Perino S, et al. Mol Cancer Ther. 2020 Aug;19(8):1613-1622. doi: 10.1158/1535-7163.MCT-19-0964. Epub 2020 Jun 4. Mol Cancer Ther. 2020. PMID: 32499300
Discovery of an SSTR2-Targeting Maytansinoid Conjugate (PEN-221) with Potent Activity in Vitro and in Vivo.
White BH, Whalen K, Kriksciukaite K, Alargova R, Au Yeung T, Bazinet P, Brockman A, DuPont M, Oller H, Lemelin CA, Lim Soo P, Moreau B, Perino S, Quinn JM, Sharma G, Shinde R, Sweryda-Krawiec B, Wooster R, Bilodeau MT. White BH, et al. Among authors: perino s. J Med Chem. 2019 Mar 14;62(5):2708-2719. doi: 10.1021/acs.jmedchem.8b02036. Epub 2019 Feb 28. J Med Chem. 2019. PMID: 30735385
23814, an Inhibitory Antibody of Ligand-Mediated Notch1 Activation, Modulates Angiogenesis and Inhibits Tumor Growth without Gastrointestinal Toxicity.
Proia T, Jiang F, Bell A, Nicoletti R, Kong L, Kreuter K, Poling L, Winston WM, Flaherty M, Weiler S, Perino S, O'Hagan R, Lin J, Gyuris J, Okamura H. Proia T, et al. Among authors: perino s. Mol Cancer Ther. 2015 Aug;14(8):1858-67. doi: 10.1158/1535-7163.MCT-14-1104. Epub 2015 May 20. Mol Cancer Ther. 2015. PMID: 25995436
Total synthesis of 6-deoxypladienolide D and Assessment of Splicing Inhibitory Activity in a Mutant SF3B1 cancer cell line.
Arai K, Buonamici S, Chan B, Corson L, Endo A, Gerard B, Hao MH, Karr C, Kira K, Lee L, Liu X, Lowe JT, Luo T, Marcaurelle LA, Mizui Y, Nevalainen M, O'Shea MW, Park ES, Perino SA, Prajapati S, Shan M, Smith PG, Tivitmahaisoon P, Wang JY, Warmuth M, Wu KM, Yu L, Zhang H, Zheng GZ, Keaney GF. Arai K, et al. Among authors: perino sa. Org Lett. 2014 Nov 7;16(21):5560-3. doi: 10.1021/ol502556c. Epub 2014 Oct 26. Org Lett. 2014. PMID: 25376106
Composition of Guayule (Parthenium argentatum Gray) resin.
Rousset A, Ginies C, Chevallier O, Martinez-Vazquez M, Amor A, Dorget M, Chemat F, Perino S. Rousset A, et al. Among authors: perino s. Sci Rep. 2023 Feb 28;13(1):3395. doi: 10.1038/s41598-023-29524-w. Sci Rep. 2023. PMID: 36854959 Free PMC article.
Solvent-Free Microwave Extraction of Thymus mastichina Essential Oil: Influence on Their Chemical Composition and on the Antioxidant and Antimicrobial Activities.
Araujo ARTS, Périno S, Fernandez X, Cunha C, Rodrigues M, Ribeiro MP, Jordao L, Silva LA, Rodilla J, Coutinho P, Chemat F. Araujo ARTS, et al. Among authors: perino s. Pharmaceuticals (Basel). 2021 Jul 22;14(8):709. doi: 10.3390/ph14080709. Pharmaceuticals (Basel). 2021. PMID: 34451806 Free PMC article.
22 results