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Targeting the Somatostatin Receptor 2 with the Miniaturized Drug Conjugate, PEN-221: A Potent and Novel Therapeutic for the Treatment of Small Cell Lung Cancer.
Mol Cancer Ther. 2019 Nov;18(11):1926-1936. doi: 10.1158/1535-7163.MCT-19-0022.
Mol Cancer Ther. 2019.
PMID: 31649014
Discovery of an SSTR2-Targeting Maytansinoid Conjugate (PEN-221) with Potent Activity in Vitro and in Vivo.
White BH, Whalen K, Kriksciukaite K, Alargova R, Au Yeung T, Bazinet P, Brockman A, DuPont M, Oller H, Lemelin CA, Lim Soo P, Moreau B, Perino S, Quinn JM, Sharma G, Shinde R, Sweryda-Krawiec B, Wooster R, Bilodeau MT.
White BH, et al. Among authors: kriksciukaite k.
J Med Chem. 2019 Mar 14;62(5):2708-2719. doi: 10.1021/acs.jmedchem.8b02036. Epub 2019 Feb 28.
J Med Chem. 2019.
PMID: 30735385
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Novel Miniaturized Drug Conjugate Leverages HSP90-driven Tumor Accumulation to Overcome PI3K Inhibitor Delivery Challenges to Solid Tumors.
Perino S, Moreau B, Freda J, Cirello A, White BH, Quinn JM, Kriksciukaite K, Someshwar A, Romagnoli J, Robinson M, Movassaghian S, Cipriani T, Wooster R, Bilodeau MT, Whalen KA.
Perino S, et al. Among authors: kriksciukaite k.
Mol Cancer Ther. 2020 Aug;19(8):1613-1622. doi: 10.1158/1535-7163.MCT-19-0964. Epub 2020 Jun 4.
Mol Cancer Ther. 2020.
PMID: 32499300
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Simple method provides resolution of albumin, lipoprotein, free fraction, and chylomicron to enhance the utility of protein binding assays.
Brockman AH, Oller HR, Moreau B, Kriksciukaite K, Bilodeau MT.
Brockman AH, et al. Among authors: kriksciukaite k.
J Med Chem. 2015 Feb 12;58(3):1420-5. doi: 10.1021/jm501748h. Epub 2015 Jan 28.
J Med Chem. 2015.
PMID: 25587854
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Prodrugs of pioglitazone for extended-release (XR) injectable formulations.
Sanrame CN, Remenar JF, Blumberg LC, Waters J, Dean RL, Dong N, Kriksciukaite K, Cao P, Almarsson O.
Sanrame CN, et al. Among authors: kriksciukaite k.
Mol Pharm. 2014 Oct 6;11(10):3617-23. doi: 10.1021/mp500359a. Epub 2014 Sep 9.
Mol Pharm. 2014.
PMID: 25157965
Free article.
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Route of administration affects the ability of naltrexone to reduce amphetamine-potentiated brain stimulation reward in rats.
Todtenkopf MS, O'Neill KS, Kriksciukaite K, Turncliff RZ, Dean RL, Ostrovsky-Day I, Deaver DR.
Todtenkopf MS, et al. Among authors: kriksciukaite k.
Addict Biol. 2009 Sep;14(4):408-18. doi: 10.1111/j.1369-1600.2009.00161.x. Epub 2009 Jun 1.
Addict Biol. 2009.
PMID: 19489752
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Overriding the blockade of antinociceptive actions of opioids in rats treated with extended-release naltrexone.
Dean RL, Todtenkopf MS, Deaver DR, Arastu MF, Dong N, Reitano K, O'Driscoll K, Kriksciukaite K, Gastfriend DR.
Dean RL, et al. Among authors: kriksciukaite k.
Pharmacol Biochem Behav. 2008 Jun;89(4):515-22. doi: 10.1016/j.pbb.2008.02.006. Epub 2008 Feb 11.
Pharmacol Biochem Behav. 2008.
PMID: 18342360
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