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Targeting the Somatostatin Receptor 2 with the Miniaturized Drug Conjugate, PEN-221: A Potent and Novel Therapeutic for the Treatment of Small Cell Lung Cancer.
Whalen KA, White BH, Quinn JM, Kriksciukaite K, Alargova R, Au Yeung TP, Bazinet P, Brockman A, DuPont MM, Oller H, Gifford J, Lemelin CA, Lim Soo P, Perino S, Moreau B, Sharma G, Shinde R, Sweryda-Krawiec B, Bilodeau MT, Wooster R. Whalen KA, et al. Among authors: brockman a. Mol Cancer Ther. 2019 Nov;18(11):1926-1936. doi: 10.1158/1535-7163.MCT-19-0022. Mol Cancer Ther. 2019. PMID: 31649014
Discovery of an SSTR2-Targeting Maytansinoid Conjugate (PEN-221) with Potent Activity in Vitro and in Vivo.
White BH, Whalen K, Kriksciukaite K, Alargova R, Au Yeung T, Bazinet P, Brockman A, DuPont M, Oller H, Lemelin CA, Lim Soo P, Moreau B, Perino S, Quinn JM, Sharma G, Shinde R, Sweryda-Krawiec B, Wooster R, Bilodeau MT. White BH, et al. Among authors: brockman a. J Med Chem. 2019 Mar 14;62(5):2708-2719. doi: 10.1021/acs.jmedchem.8b02036. Epub 2019 Feb 28. J Med Chem. 2019. PMID: 30735385
Assessing Toxicokinetic Uncertainty and Variability in Risk Prioritization.
Wambaugh JF, Wetmore BA, Ring CL, Nicolas CI, Pearce RG, Honda GS, Dinallo R, Angus D, Gilbert J, Sierra T, Badrinarayanan A, Snodgrass B, Brockman A, Strock C, Setzer RW, Thomas RS. Wambaugh JF, et al. Among authors: brockman a. Toxicol Sci. 2019 Dec 1;172(2):235-251. doi: 10.1093/toxsci/kfz205. Toxicol Sci. 2019. PMID: 31532498 Free PMC article.
IL-8 Instructs Macrophage Identity in Lateral Ventricle Contacting Glioblastoma.
Medina S, Brockman AA, Cross CE, Hayes MJ, Mobley BC, Mistry AM, Chotai S, Weaver KD, Thompson RC, Chambless LB, Ihrie RA, Irish JM. Medina S, et al. Among authors: brockman aa. bioRxiv [Preprint]. 2024 Mar 30:2024.03.29.587030. doi: 10.1101/2024.03.29.587030. bioRxiv. 2024. PMID: 38585888 Free PMC article. Preprint.
113 results