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p38γ MAPK contributes to left ventricular remodeling after pathologic stress and disinhibits calpain through phosphorylation of calpastatin.
Loonat AA, Martin ED, Sarafraz-Shekary N, Tilgner K, Hertz NT, Levin R, Shokat KM, Burlingame AL, Arabacilar P, Uddin S, Thomas M, Marber MS, Clark JE. Loonat AA, et al. Among authors: martin ed. FASEB J. 2019 Dec;33(12):13131-13144. doi: 10.1096/fj.201701545R. Epub 2019 Oct 22. FASEB J. 2019. PMID: 31638431 Free PMC article.
p38 MAPK in cardioprotection - are we there yet?
Martin ED, Bassi R, Marber MS. Martin ED, et al. Br J Pharmacol. 2015 Apr;172(8):2101-13. doi: 10.1111/bph.12901. Epub 2014 Nov 24. Br J Pharmacol. 2015. PMID: 25204838 Free PMC article. Review.
The TAB1-p38α complex aggravates myocardial injury and can be targeted by small molecules.
De Nicola GF, Bassi R, Nichols C, Fernandez-Caggiano M, Golforoush PA, Thapa D, Anderson R, Martin ED, Verma S, Kleinjung J, Laing A, Hutchinson JP, Eaton P, Clark J, Marber MS. De Nicola GF, et al. Among authors: martin ed. JCI Insight. 2018 Aug 23;3(16):e121144. doi: 10.1172/jci.insight.121144. eCollection 2018 Aug 23. JCI Insight. 2018. PMID: 30135318 Free PMC article.
Disulfide-activated protein kinase G Iα regulates cardiac diastolic relaxation and fine-tunes the Frank-Starling response.
Scotcher J, Prysyazhna O, Boguslavskyi A, Kistamas K, Hadgraft N, Martin ED, Worthington J, Rudyk O, Rodriguez Cutillas P, Cuello F, Shattock MJ, Marber MS, Conte MR, Greenstein A, Greensmith DJ, Venetucci L, Timms JF, Eaton P. Scotcher J, et al. Among authors: martin ed. Nat Commun. 2016 Oct 26;7:13187. doi: 10.1038/ncomms13187. Nat Commun. 2016. PMID: 27782102 Free PMC article.
In mammalian skeletal muscle, phosphorylation of TOMM22 by protein kinase CSNK2/CK2 controls mitophagy.
Kravic B, Harbauer AB, Romanello V, Simeone L, Vögtle FN, Kaiser T, Straubinger M, Huraskin D, Böttcher M, Cerqua C, Martin ED, Poveda-Huertes D, Buttgereit A, Rabalski AJ, Heuss D, Rudolf R, Friedrich O, Litchfield D, Marber M, Salviati L, Mougiakakos D, Neuhuber W, Sandri M, Meisinger C, Hashemolhosseini S. Kravic B, et al. Among authors: martin ed. Autophagy. 2018;14(2):311-335. doi: 10.1080/15548627.2017.1403716. Epub 2018 Feb 1. Autophagy. 2018. PMID: 29165030 Free PMC article.
SIRT2 Inhibition Rescues Neurodegenerative Pathology but Increases Systemic Inflammation in a Transgenic Mouse Model of Alzheimer's Disease.
Sola-Sevilla N, Mesa-Lombardo A, Aleixo M, Expósito S, Diaz-Perdigón T, Azqueta A, Zamani F, Suzuki T, Maioli S, Eroli F, Matton A, Ramírez MJ, Solas M, Tordera RM, Martín ED, Puerta E. Sola-Sevilla N, et al. Among authors: martin ed. J Neuroimmune Pharmacol. 2023 Sep;18(3):529-550. doi: 10.1007/s11481-023-10084-9. Epub 2023 Sep 12. J Neuroimmune Pharmacol. 2023. PMID: 37698780 Free PMC article.
149 results