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Enantiomeric glycosylated cationic block co-beta-peptides eradicate Staphylococcus aureus biofilms and antibiotic-tolerant persisters.
Zhang K, Du Y, Si Z, Liu Y, Turvey ME, Raju C, Keogh D, Ruan L, Jothy SL, Reghu S, Marimuthu K, De PP, Ng OT, Mediavilla JR, Kreiswirth BN, Chi YR, Ren J, Tam KC, Liu XW, Duan H, Zhu Y, Mu Y, Hammond PT, Bazan GC, Pethe K, Chan-Park MB. Zhang K, et al. Among authors: bazan gc. Nat Commun. 2019 Oct 21;10(1):4792. doi: 10.1038/s41467-019-12702-8. Nat Commun. 2019. PMID: 31636263 Free PMC article.
A Glycosylated Cationic Block Poly(β-peptide) Reverses Intrinsic Antibiotic Resistance in All ESKAPE Gram-Negative Bacteria.
Si Z, Lim HW, Tay MYF, Du Y, Ruan L, Qiu H, Zamudio-Vazquez R, Reghu S, Chen Y, Tiong WS, Marimuthu K, De PP, Ng OT, Zhu Y, Gan YH, Chi YR, Duan H, Bazan GC, Greenberg EP, Chan-Park MB, Pethe K. Si Z, et al. Among authors: bazan gc. Angew Chem Int Ed Engl. 2020 Apr 20;59(17):6819-6826. doi: 10.1002/anie.201914304. Epub 2020 Feb 19. Angew Chem Int Ed Engl. 2020. PMID: 32011781
Membrane adaptation limitations in Enterococcus faecalis underlie sensitivity and the inability to develop significant resistance to conjugated oligoelectrolytes.
Chilambi GS, Gao IH, Yoon BK, Park S, Kawakami LM, Ravikumar V, Chan-Park MB, Cho NJ, Bazan GC, Kline KA, Rice SA, Hinks J. Chilambi GS, et al. Among authors: bazan gc. RSC Adv. 2018 Mar 13;8(19):10284-10293. doi: 10.1039/c7ra11823f. eCollection 2018 Mar 13. RSC Adv. 2018. PMID: 35540442 Free PMC article.
326 results