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Induced cardiac progenitor cells repopulate decellularized mouse heart scaffolds and differentiate to generate cardiac tissue.
Alexanian RA, Mahapatra K, Lang D, Vaidyanathan R, Markandeya YS, Gill RK, Zhai AJ, Dhillon A, Lea MR, Abozeid S, Schmuck EG, Raval AN, Eckhardt LL, Glukhov AV, Lalit PA, Kamp TJ. Alexanian RA, et al. Among authors: eckhardt ll. Biochim Biophys Acta Mol Cell Res. 2020 Mar;1867(3):118559. doi: 10.1016/j.bbamcr.2019.118559. Epub 2019 Oct 18. Biochim Biophys Acta Mol Cell Res. 2020. PMID: 31634503 Free PMC article.
Specific serine proteases selectively damage KCNH2 (hERG1) potassium channels and I(Kr).
Rajamani S, Anderson CL, Valdivia CR, Eckhardt LL, Foell JD, Robertson GA, Kamp TJ, Makielski JC, Anson BD, January CT. Rajamani S, et al. Among authors: eckhardt ll. Am J Physiol Heart Circ Physiol. 2006 Mar;290(3):H1278-88. doi: 10.1152/ajpheart.00777.2005. Epub 2005 Oct 14. Am J Physiol Heart Circ Physiol. 2006. PMID: 16227340 Free article.
hERG 1b is critical for human cardiac repolarization.
Jones DK, Liu F, Vaidyanathan R, Eckhardt LL, Trudeau MC, Robertson GA. Jones DK, et al. Among authors: eckhardt ll. Proc Natl Acad Sci U S A. 2014 Dec 16;111(50):18073-7. doi: 10.1073/pnas.1414945111. Epub 2014 Dec 1. Proc Natl Acad Sci U S A. 2014. PMID: 25453103 Free PMC article.
IK1-enhanced human-induced pluripotent stem cell-derived cardiomyocytes: an improved cardiomyocyte model to investigate inherited arrhythmia syndromes.
Vaidyanathan R, Markandeya YS, Kamp TJ, Makielski JC, January CT, Eckhardt LL. Vaidyanathan R, et al. Among authors: eckhardt ll. Am J Physiol Heart Circ Physiol. 2016 Jun 1;310(11):H1611-21. doi: 10.1152/ajpheart.00481.2015. Epub 2016 Apr 8. Am J Physiol Heart Circ Physiol. 2016. PMID: 27059077 Free PMC article.
Genetic Loss of IK1 Causes Adrenergic-Induced Phase 3 Early Afterdepolariz ations and Polymorphic and Bidirectional Ventricular Tachycardia.
Reilly L, Alvarado FJ, Lang D, Abozeid S, Van Ert H, Spellman C, Warden J, Makielski JC, Glukhov AV, Eckhardt LL. Reilly L, et al. Among authors: eckhardt ll. Circ Arrhythm Electrophysiol. 2020 Sep;13(9):e008638. doi: 10.1161/CIRCEP.120.008638. Epub 2020 Aug 4. Circ Arrhythm Electrophysiol. 2020. PMID: 32931337 Free PMC article.
63 results