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Senescent human melanocytes drive skin ageing via paracrine telomere dysfunction.
Victorelli S, Lagnado A, Halim J, Moore W, Talbot D, Barrett K, Chapman J, Birch J, Ogrodnik M, Meves A, Pawlikowski JS, Jurk D, Adams PD, van Heemst D, Beekman M, Slagboom PE, Gunn DA, Passos JF. Victorelli S, et al. Among authors: beekman m. EMBO J. 2019 Dec 2;38(23):e101982. doi: 10.15252/embj.2019101982. Epub 2019 Oct 21. EMBO J. 2019. PMID: 31633821 Free PMC article.
Combined association and linkage analysis applied to the APOE locus.
Beekman M, Posthuma D, Heijmans BT, Lakenberg N, Suchiman HE, Snieder H, de Knijff P, Frants RR, van Ommen GJ, Kluft C, Vogler GP, Slagboom PE, Boomsma DI. Beekman M, et al. Genet Epidemiol. 2004 May;26(4):328-37. doi: 10.1002/gepi.10318. Genet Epidemiol. 2004. PMID: 15095392 Free article.
Reduced insulin/IGF-1 signalling and human longevity.
van Heemst D, Beekman M, Mooijaart SP, Heijmans BT, Brandt BW, Zwaan BJ, Slagboom PE, Westendorp RG. van Heemst D, et al. Among authors: beekman m. Aging Cell. 2005 Apr;4(2):79-85. doi: 10.1111/j.1474-9728.2005.00148.x. Aging Cell. 2005. PMID: 15771611 Free article.
Lipoprotein particle profiles mark familial and sporadic human longevity.
Heijmans BT, Beekman M, Houwing-Duistermaat JJ, Cobain MR, Powell J, Blauw GJ, van der Ouderaa F, Westendorp RG, Slagboom PE. Heijmans BT, et al. Among authors: beekman m. PLoS Med. 2006 Dec;3(12):e495. doi: 10.1371/journal.pmed.0030495. PLoS Med. 2006. PMID: 17194192 Free PMC article.
Molecular epidemiology, candidate genes versus genome-wide scans.
Slagboom PE, Heijmans BT, Beekman M, Meulenbelt I. Slagboom PE, et al. Among authors: beekman m. Genes Nutr. 2007 Oct;2(1):27-9. doi: 10.1007/s12263-007-0002-0. Genes Nutr. 2007. PMID: 18850134 Free PMC article. No abstract available.
Nonagenarian siblings and their offspring display lower risk of mortality and morbidity than sporadic nonagenarians: The Leiden Longevity Study.
Westendorp RG, van Heemst D, Rozing MP, Frölich M, Mooijaart SP, Blauw GJ, Beekman M, Heijmans BT, de Craen AJ, Slagboom PE; Leiden Longevity Study Group. Westendorp RG, et al. Among authors: beekman m. J Am Geriatr Soc. 2009 Sep;57(9):1634-7. doi: 10.1111/j.1532-5415.2009.02381.x. Epub 2009 Jul 17. J Am Geriatr Soc. 2009. PMID: 19682117
381 results