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Mitochondrial oxidative stress and respiratory chain dysfunction account for liver toxicity during amiodarone but not dronedarone administration.
Serviddio G, Bellanti F, Giudetti AM, Gnoni GV, Capitanio N, Tamborra R, Romano AD, Quinto M, Blonda M, Vendemiale G, Altomare E. Serviddio G, et al. Among authors: tamborra r. Free Radic Biol Med. 2011 Dec 15;51(12):2234-42. doi: 10.1016/j.freeradbiomed.2011.09.004. Epub 2011 Sep 17. Free Radic Biol Med. 2011. PMID: 21971348
Many faces of mitochondrial uncoupling during age: damage or defense?
Bellanti F, Romano AD, Giudetti AM, Rollo T, Blonda M, Tamborra R, Vendemiale G, Serviddio G. Bellanti F, et al. Among authors: tamborra r. J Gerontol A Biol Sci Med Sci. 2013 Aug;68(8):892-902. doi: 10.1093/gerona/gls332. Epub 2013 Jan 4. J Gerontol A Biol Sci Med Sci. 2013. PMID: 23292290
Propofol but not sevoflurane prevents mitochondrial dysfunction and oxidative stress by limiting HIF-1α activation in hepatic ischemia/reperfusion injury.
Bellanti F, Mirabella L, Mitarotonda D, Blonda M, Tamborra R, Cinnella G, Fersini A, Ambrosi A, Dambrosio M, Vendemiale G, Serviddio G. Bellanti F, et al. Among authors: tamborra r. Free Radic Biol Med. 2016 Jul;96:323-33. doi: 10.1016/j.freeradbiomed.2016.05.002. Epub 2016 May 3. Free Radic Biol Med. 2016. PMID: 27154980
26 results