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Reactive γ-ketoaldehydes promote protein misfolding and preamyloid oligomer formation in rapidly-activated atrial cells.
Sidorova TN, Yermalitskaya LV, Mace LC, Wells KS, Boutaud O, Prinsen JK, Davies SS, Roberts LJ 2nd, Dikalov SI, Glabe CG, Amarnath V, Barnett JV, Murray KT. Sidorova TN, et al. Among authors: amarnath v. J Mol Cell Cardiol. 2015 Feb;79:295-302. doi: 10.1016/j.yjmcc.2014.11.013. Epub 2014 Nov 18. J Mol Cell Cardiol. 2015. PMID: 25463275 Free PMC article.
Targeting of reactive isolevuglandins in mitochondrial dysfunction and inflammation.
Mayorov V, Uchakin P, Amarnath V, Panov AV, Bridges CC, Uzhachenko R, Zackert B, Moore CS, Davies S, Dikalova A, Dikalov S. Mayorov V, et al. Among authors: amarnath v. Redox Biol. 2019 Sep;26:101300. doi: 10.1016/j.redox.2019.101300. Epub 2019 Aug 14. Redox Biol. 2019. PMID: 31437812 Free PMC article.
Modified sites and functional consequences of 4-oxo-2-nonenal adducts in HDL that are elevated in familial hypercholesterolemia.
May-Zhang LS, Yermalitsky V, Melchior JT, Morris J, Tallman KA, Borja MS, Pleasent T, Amarnath V, Song W, Yancey PG, Davidson WS, Linton MF, Davies SS. May-Zhang LS, et al. Among authors: amarnath v. J Biol Chem. 2019 Dec 13;294(50):19022-19033. doi: 10.1074/jbc.RA119.009424. Epub 2019 Oct 30. J Biol Chem. 2019. PMID: 31666337 Free PMC article.
Highly Reactive Isolevuglandins Promote Atrial Fibrillation Caused by Hypertension.
Prinsen JK, Kannankeril PJ, Sidorova TN, Yermalitskaya LV, Boutaud O, Zagol-Ikapitte I, Barnett JV, Murphy MB, Subati T, Stark JM, Christopher IL, Jafarian-Kerman SR, Saleh MA, Norlander AE, Loperena R, Atkinson JB, Fogo AB, Luther JM, Amarnath V, Davies SS, Kirabo A, Madhur MS, Harrison DG, Murray KT. Prinsen JK, et al. Among authors: amarnath v. JACC Basic Transl Sci. 2020 May 27;5(6):602-615. doi: 10.1016/j.jacbts.2020.04.004. eCollection 2020 Jun. JACC Basic Transl Sci. 2020. PMID: 32613146 Free PMC article.
113 results