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Page 1
Identification of atrial fibrillation associated genes and functional non-coding variants.
van Ouwerkerk AF, Bosada FM, van Duijvenboden K, Hill MC, Montefiori LE, Scholman KT, Liu J, de Vries AAF, Boukens BJ, Ellinor PT, Goumans MJTH, Efimov IR, Nobrega MA, Barnett P, Martin JF, Christoffels VM. van Ouwerkerk AF, et al. Among authors: scholman kt. Nat Commun. 2019 Oct 18;10(1):4755. doi: 10.1038/s41467-019-12721-5. Nat Commun. 2019. PMID: 31628324 Free PMC article.
Variant Intronic Enhancer Controls SCN10A-short Expression and Heart Conduction.
Man JCK, Bosada FM, Scholman KT, Offerhaus JA, Walsh R, van Duijvenboden K, van Eif VWW, Bezzina CR, Verkerk AO, Boukens BJ, Barnett P, Christoffels VM. Man JCK, et al. Among authors: scholman kt. Circulation. 2021 Jul 20;144(3):229-242. doi: 10.1161/CIRCULATIONAHA.121.054083. Epub 2021 Apr 29. Circulation. 2021. PMID: 33910361
Patient-Specific TBX5-G125R Variant Induces Profound Transcriptional Deregulation and Atrial Dysfunction.
van Ouwerkerk AF, Bosada FM, van Duijvenboden K, Houweling AC, Scholman KT, Wakker V, Allaart CP, Uhm JS, Mathijssen IB, Baartscheer T, Postma AV, Barnett P, Verkerk AO, Boukens BJ, Christoffels VM. van Ouwerkerk AF, et al. Among authors: scholman kt. Circulation. 2022 Feb 22;145(8):606-619. doi: 10.1161/CIRCULATIONAHA.121.054347. Epub 2022 Feb 3. Circulation. 2022. PMID: 35113653 Free PMC article.
Neurokinin-3 receptor activation selectively prolongs atrial refractoriness by inhibition of a background K+ channel.
Veldkamp MW, Geuzebroek GSC, Baartscheer A, Verkerk AO, Schumacher CA, Suarez GG, Berger WR, Casini S, van Amersfoorth SCM, Scholman KT, Driessen AHG, Belterman CNW, van Ginneken ACG, de Groot JR, de Bakker JMT, Remme CA, Boukens BJ, Coronel R. Veldkamp MW, et al. Among authors: scholman kt. Nat Commun. 2018 Oct 19;9(1):4357. doi: 10.1038/s41467-018-06530-5. Nat Commun. 2018. PMID: 30341287 Free PMC article.
Tomo-Seq Identifies SOX9 as a Key Regulator of Cardiac Fibrosis During Ischemic Injury.
Lacraz GPA, Junker JP, Gladka MM, Molenaar B, Scholman KT, Vigil-Garcia M, Versteeg D, de Ruiter H, Vermunt MW, Creyghton MP, Huibers MMH, de Jonge N, van Oudenaarden A, van Rooij E. Lacraz GPA, et al. Among authors: scholman kt. Circulation. 2017 Oct 10;136(15):1396-1409. doi: 10.1161/CIRCULATIONAHA.117.027832. Epub 2017 Jul 19. Circulation. 2017. PMID: 28724751
Genome-wide analysis reveals NRP1 as a direct HIF1α-E2F7 target in the regulation of motorneuron guidance in vivo.
de Bruin A, A Cornelissen PW, Kirchmaier BC, Mokry M, Iich E, Nirmala E, Liang KH, D Végh AM, Scholman KT, Groot Koerkamp MJ, Holstege FC, Cuppen E, Schulte-Merker S, Bakker WJ. de Bruin A, et al. Among authors: scholman kt. Nucleic Acids Res. 2016 May 5;44(8):3549-66. doi: 10.1093/nar/gkv1471. Epub 2015 Dec 17. Nucleic Acids Res. 2016. PMID: 26681691 Free PMC article.