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Impaired chloride homeostasis in epilepsy: Molecular basis, impact on treatment, and current treatment approaches.
Pharmacol Ther. 2020 Jan;205:107422. doi: 10.1016/j.pharmthera.2019.107422. Epub 2019 Oct 15.
Pharmacol Ther. 2020.
PMID: 31626872
Review.
Functional characterization of novel bumetanide derivatives for epilepsy treatment.
Auer T, Schreppel P, Erker T, Schwarzer C.
Auer T, et al. Among authors: schreppel p.
Neuropharmacology. 2020 Jan 1;162:107754. doi: 10.1016/j.neuropharm.2019.107754. Epub 2019 Aug 30.
Neuropharmacology. 2020.
PMID: 31476353
Free article.
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The bumetanide prodrug BUM5, but not bumetanide, potentiates the antiseizure effect of phenobarbital in adult epileptic mice.
Erker T, Brandt C, Töllner K, Schreppel P, Twele F, Schidlitzki A, Löscher W.
Erker T, et al. Among authors: schreppel p.
Epilepsia. 2016 May;57(5):698-705. doi: 10.1111/epi.13346. Epub 2016 Feb 27.
Epilepsia. 2016.
PMID: 26921222
Free article.
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A Novel Na+-K+-Cl- Cotransporter 1 Inhibitor STS66* Reduces Brain Damage in Mice After Ischemic Stroke.
Huang H, Bhuiyan MIH, Jiang T, Song S, Shankar S, Taheri T, Li E, Schreppel P, Hintersteininger M, Yang SS, Lin SH, Molyneaux BJ, Zhang Z, Erker T, Sun D.
Huang H, et al. Among authors: schreppel p.
Stroke. 2019 Apr;50(4):1021-1025. doi: 10.1161/STROKEAHA.118.024287.
Stroke. 2019.
PMID: 30862257
Free PMC article.
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Role of NKCC1 Activity in Glioma K+ Homeostasis and Cell Growth: New Insights With the Bumetanide-Derivative STS66.
Luo L, Wang J, Ding D, Hasan MN, Yang SS, Lin SH, Schreppel P, Sun B, Yin Y, Erker T, Sun D.
Luo L, et al. Among authors: schreppel p.
Front Physiol. 2020 Jul 31;11:911. doi: 10.3389/fphys.2020.00911. eCollection 2020.
Front Physiol. 2020.
PMID: 32848856
Free PMC article.
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A Novel Genistein Prodrug: Design, Synthesis and Bioactivity on Mouse RAW264.7 Macrophages.
Kloesch B, Loebsch S, Breitenbach J, Goldhahn K, Handler N, Schreppel P, Erker T.
Kloesch B, et al. Among authors: schreppel p.
Nat Prod Commun. 2016 Oct;11(10):1437-1440.
Nat Prod Commun. 2016.
PMID: 30549594
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