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NLRP3 inflammasome suppression improves longevity and prevents cardiac aging in male mice.
Marín-Aguilar F, Lechuga-Vieco AV, Alcocer-Gómez E, Castejón-Vega B, Lucas J, Garrido C, Peralta-Garcia A, Pérez-Pulido AJ, Varela-López A, Quiles JL, Ryffel B, Flores I, Bullón P, Ruiz-Cabello J, Cordero MD. Marín-Aguilar F, et al. Among authors: ryffel b. Aging Cell. 2020 Jan;19(1):e13050. doi: 10.1111/acel.13050. Epub 2019 Oct 18. Aging Cell. 2020. PMID: 31625260 Free PMC article.
AMPK Phosphorylation Modulates Pain by Activation of NLRP3 Inflammasome.
Bullón P, Alcocer-Gómez E, Carrión AM, Marín-Aguilar F, Garrido-Maraver J, Román-Malo L, Ruiz-Cabello J, Culic O, Ryffel B, Apetoh L, Ghiringhelli F, Battino M, Sánchez-Alcazar JA, Cordero MD. Bullón P, et al. Among authors: ryffel b. Antioxid Redox Signal. 2016 Jan 20;24(3):157-70. doi: 10.1089/ars.2014.6120. Epub 2015 Sep 16. Antioxid Redox Signal. 2016. PMID: 26132721 Free PMC article.
Stress-Induced Depressive Behaviors Require a Functional NLRP3 Inflammasome.
Alcocer-Gómez E, Ulecia-Morón C, Marín-Aguilar F, Rybkina T, Casas-Barquero N, Ruiz-Cabello J, Ryffel B, Apetoh L, Ghiringhelli F, Bullón P, Sánchez-Alcazar JA, Carrión AM, Cordero MD. Alcocer-Gómez E, et al. Among authors: ryffel b. Mol Neurobiol. 2016 Sep;53(7):4874-82. doi: 10.1007/s12035-015-9408-7. Epub 2015 Sep 11. Mol Neurobiol. 2016. PMID: 26362308
NLRP3 Inflammasome Inhibition by MCC950 in Aged Mice Improves Health via Enhanced Autophagy and PPARα Activity.
Marín-Aguilar F, Castejón-Vega B, Alcocer-Gómez E, Lendines-Cordero D, Cooper MA, de la Cruz P, Andújar-Pulido E, Pérez-Alegre M, Muntané J, Pérez-Pulido AJ, Ryffel B, Robertson AAB, Ruiz-Cabello J, Bullón P, Cordero MD. Marín-Aguilar F, et al. Among authors: ryffel b. J Gerontol A Biol Sci Med Sci. 2020 Jul 13;75(8):1457-1464. doi: 10.1093/gerona/glz239. J Gerontol A Biol Sci Med Sci. 2020. PMID: 31603987
Blockade of the NLRP3 inflammasome improves metabolic health and lifespan in obese mice.
Cañadas-Lozano D, Marín-Aguilar F, Castejón-Vega B, Ryffel B, Navarro-Pando JM, Ruiz-Cabello J, Alcocer-Gómez E, Bullón P, Cordero MD. Cañadas-Lozano D, et al. Among authors: ryffel b. Geroscience. 2020 Apr;42(2):715-725. doi: 10.1007/s11357-019-00151-6. Epub 2020 Jan 23. Geroscience. 2020. PMID: 31975052 Free PMC article.
Inhibition of the NLRP3 inflammasome prevents ovarian aging.
Navarro-Pando JM, Alcocer-Gómez E, Castejón-Vega B, Navarro-Villarán E, Condés-Hervás M, Mundi-Roldan M, Muntané J, Pérez-Pulido AJ, Bullon P, Wang C, Hoffman HM, Sanz A, Mbalaviele G, Ryffel B, Cordero MD. Navarro-Pando JM, et al. Among authors: ryffel b. Sci Adv. 2021 Jan 1;7(1):eabc7409. doi: 10.1126/sciadv.abc7409. Print 2021 Jan. Sci Adv. 2021. PMID: 33523841 Free PMC article.
NLRP3-inflammasome inhibition prevents high fat and high sugar diets-induced heart damage through autophagy induction.
Pavillard LE, Cañadas-Lozano D, Alcocer-Gómez E, Marín-Aguilar F, Pereira S, Robertson AAB, Muntané J, Ryffel B, Cooper MA, Quiles JL, Bullón P, Ruiz-Cabello J, Cordero MD. Pavillard LE, et al. Among authors: ryffel b. Oncotarget. 2017 Sep 8;8(59):99740-99756. doi: 10.18632/oncotarget.20763. eCollection 2017 Nov 21. Oncotarget. 2017. PMID: 29245937 Free PMC article.
Induction of NLRP3 Inflammasome Activation by Heme in Human Endothelial Cells.
Erdei J, Tóth A, Balogh E, Nyakundi BB, Bányai E, Ryffel B, Paragh G, Cordero MD, Jeney V. Erdei J, et al. Among authors: ryffel b. Oxid Med Cell Longev. 2018 Mar 20;2018:4310816. doi: 10.1155/2018/4310816. eCollection 2018. Oxid Med Cell Longev. 2018. PMID: 29743981 Free PMC article.
548 results