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Novel compounds with potent CDK9 inhibitory activity for the treatment of myeloma.
Czudor Z, Balogh M, Bánhegyi P, Boros S, Breza N, Dobos J, Fábián M, Horváth Z, Illyés E, Markó P, Sipos A, Szántai-Kis C, Szokol B, Őrfi L. Czudor Z, et al. Among authors: dobos j. Bioorg Med Chem Lett. 2018 Feb 15;28(4):769-773. doi: 10.1016/j.bmcl.2018.01.002. Epub 2018 Jan 2. Bioorg Med Chem Lett. 2018. PMID: 29329658
EGFR Alterations Influence the Cetuximab Treatment Response and c-MET Tyrosine-Kinase Inhibitor Sensitivity in Experimental Head and Neck Squamous Cell Carcinomas.
Nelhűbel GA, Cserepes M, Szabó B, Türk D, Kárpáti A, Kenessey I, Rásó E, Barbai T, Hegedűs Z, László V, Szokol B, Dobos J, Őrfi L, Tóvári J. Nelhűbel GA, et al. Among authors: dobos j. Pathol Oncol Res. 2021 May 3;27:620256. doi: 10.3389/pore.2021.620256. eCollection 2021. Pathol Oncol Res. 2021. PMID: 34257586 Free PMC article.
Targeted drug combination therapy design based on driver genes.
Zsákai L, Sipos A, Dobos J, Erős D, Szántai-Kis C, Bánhegyi P, Pató J, Őrfi L, Matula Z, Mikala G, Kéri G, Peták I, Vályi-Nagy I. Zsákai L, et al. Among authors: dobos j. Oncotarget. 2019 Sep 3;10(51):5255-5266. doi: 10.18632/oncotarget.26985. eCollection 2019 Sep 3. Oncotarget. 2019. PMID: 31523388 Free PMC article.
Inhibition of c-Met with the specific small molecule tyrosine kinase inhibitor SU11274 decreases growth and metastasis formation of experimental human melanoma.
Kenessey I, Keszthelyi M, Krámer Z, Berta J, Adám A, Dobos J, Mildner M, Flachner B, Cseh S, Barna G, Szokol B, Orfi L, Kéri G, Döme B, Klepetko W, Tímár J, Tóvári J. Kenessey I, et al. Among authors: dobos j. Curr Cancer Drug Targets. 2010 May;10(3):332-42. doi: 10.2174/156800910791190184. Curr Cancer Drug Targets. 2010. PMID: 20370683
34 results