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Page 1
IRF2 is a master regulator of human keratinocyte stem cell fate.
Mercado N, Schutzius G, Kolter C, Estoppey D, Bergling S, Roma G, Gubser Keller C, Nigsch F, Salathe A, Terranova R, Reece-Hoyes J, Alford J, Russ C, Knehr J, Hoepfner D, Aebi A, Ruffner H, Beck TC, Jagannathan S, Olson CM, Sheppard HE, Elsarrag SZ, Bouwmeester T, Frederiksen M, Lohmann F, Lin CY, Kirkland S. Mercado N, et al. Among authors: hoepfner d. Nat Commun. 2019 Oct 14;10(1):4676. doi: 10.1038/s41467-019-12559-x. Nat Commun. 2019. PMID: 31611556 Free PMC article.
High-resolution chemical dissection of a model eukaryote reveals targets, pathways and gene functions.
Hoepfner D, Helliwell SB, Sadlish H, Schuierer S, Filipuzzi I, Brachat S, Bhullar B, Plikat U, Abraham Y, Altorfer M, Aust T, Baeriswyl L, Cerino R, Chang L, Estoppey D, Eichenberger J, Frederiksen M, Hartmann N, Hohendahl A, Knapp B, Krastel P, Melin N, Nigsch F, Oakeley EJ, Petitjean V, Petersen F, Riedl R, Schmitt EK, Staedtler F, Studer C, Tallarico JA, Wetzel S, Fishman MC, Porter JA, Movva NR. Hoepfner D, et al. Microbiol Res. 2014 Feb-Mar;169(2-3):107-20. doi: 10.1016/j.micres.2013.11.004. Epub 2013 Dec 1. Microbiol Res. 2014. PMID: 24360837 Free article.
Decatransin, a new natural product inhibiting protein translocation at the Sec61/SecYEG translocon.
Junne T, Wong J, Studer C, Aust T, Bauer BW, Beibel M, Bhullar B, Bruccoleri R, Eichenberger J, Estoppey D, Hartmann N, Knapp B, Krastel P, Melin N, Oakeley EJ, Oberer L, Riedl R, Roma G, Schuierer S, Petersen F, Tallarico JA, Rapoport TA, Spiess M, Hoepfner D. Junne T, et al. Among authors: hoepfner d. J Cell Sci. 2015 Mar 15;128(6):1217-29. doi: 10.1242/jcs.165746. Epub 2015 Jan 22. J Cell Sci. 2015. PMID: 25616894 Free PMC article.
Nannocystin A: an Elongation Factor 1 Inhibitor from Myxobacteria with Differential Anti-Cancer Properties.
Krastel P, Roggo S, Schirle M, Ross NT, Perruccio F, Aspesi P Jr, Aust T, Buntin K, Estoppey D, Liechty B, Mapa F, Memmert K, Miller H, Pan X, Riedl R, Thibaut C, Thomas J, Wagner T, Weber E, Xie X, Schmitt EK, Hoepfner D. Krastel P, et al. Among authors: hoepfner d. Angew Chem Int Ed Engl. 2015 Aug 24;54(35):10149-54. doi: 10.1002/anie.201505069. Epub 2015 Jul 15. Angew Chem Int Ed Engl. 2015. PMID: 26179970
FR171456 is a specific inhibitor of mammalian NSDHL and yeast Erg26p.
Helliwell SB, Karkare S, Bergdoll M, Rahier A, Leighton-Davis JR, Fioretto C, Aust T, Filipuzzi I, Frederiksen M, Gounarides J, Hoepfner D, Hofmann A, Imbert PE, Jeker R, Knochenmuss R, Krastel P, Margerit A, Memmert K, Miault CV, Rao Movva N, Muller A, Naegeli HU, Oberer L, Prindle V, Riedl R, Schuierer S, Sexton JA, Tao J, Wagner T, Yin H, Zhang J, Roggo S, Reinker S, Parker CN. Helliwell SB, et al. Among authors: hoepfner d. Nat Commun. 2015 Oct 12;6:8613. doi: 10.1038/ncomms9613. Nat Commun. 2015. PMID: 26456460 Free PMC article.
Identification of a novel NAMPT inhibitor by CRISPR/Cas9 chemogenomic profiling in mammalian cells.
Estoppey D, Hewett JW, Guy CT, Harrington E, Thomas JR, Schirle M, Cuttat R, Waldt A, Gerrits B, Yang Z, Schuierer S, Pan X, Xie K, Carbone W, Knehr J, Lindeman A, Russ C, Frias E, Hoffman GR, Varadarajan M, Ramadan N, Reece-Hoyes JS, Wang Q, Chen X, McAllister G, Roma G, Bouwmeester T, Hoepfner D. Estoppey D, et al. Among authors: hoepfner d. Sci Rep. 2017 Feb 16;7:42728. doi: 10.1038/srep42728. Sci Rep. 2017. PMID: 28205648 Free PMC article.
The Natural Product Cavinafungin Selectively Interferes with Zika and Dengue Virus Replication by Inhibition of the Host Signal Peptidase.
Estoppey D, Lee CM, Janoschke M, Lee BH, Wan KF, Dong H, Mathys P, Filipuzzi I, Schuhmann T, Riedl R, Aust T, Galuba O, McAllister G, Russ C, Spiess M, Bouwmeester T, Bonamy GMC, Hoepfner D. Estoppey D, et al. Among authors: hoepfner d. Cell Rep. 2017 Apr 18;19(3):451-460. doi: 10.1016/j.celrep.2017.03.071. Cell Rep. 2017. PMID: 28423309 Free article.
A reversible haploid mouse embryonic stem cell biobank resource for functional genomics.
Elling U, Wimmer RA, Leibbrandt A, Burkard T, Michlits G, Leopoldi A, Micheler T, Abdeen D, Zhuk S, Aspalter IM, Handl C, Liebergesell J, Hubmann M, Husa AM, Kinzer M, Schuller N, Wetzel E, van de Loo N, Martinez JAZ, Estoppey D, Riedl R, Yang F, Fu B, Dechat T, Ivics Z, Agu CA, Bell O, Blaas D, Gerhardt H, Hoepfner D, Stark A, Penninger JM. Elling U, et al. Among authors: hoepfner d. Nature. 2017 Oct 5;550(7674):114-118. doi: 10.1038/nature24027. Epub 2017 Sep 27. Nature. 2017. PMID: 28953874 Free PMC article.
CRISPR-UMI: single-cell lineage tracing of pooled CRISPR-Cas9 screens.
Michlits G, Hubmann M, Wu SH, Vainorius G, Budusan E, Zhuk S, Burkard TR, Novatchkova M, Aichinger M, Lu Y, Reece-Hoyes J, Nitsch R, Schramek D, Hoepfner D, Elling U. Michlits G, et al. Among authors: hoepfner d. Nat Methods. 2017 Dec;14(12):1191-1197. doi: 10.1038/nmeth.4466. Epub 2017 Oct 16. Nat Methods. 2017. PMID: 29039415
57 results