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Dual-Acting Cholinesterase-Human Cannabinoid Receptor 2 Ligands Show Pronounced Neuroprotection in Vitro and Overadditive and Disease-Modifying Neuroprotective Effects in Vivo.
Scheiner M, Dolles D, Gunesch S, Hoffmann M, Nabissi M, Marinelli O, Naldi M, Bartolini M, Petralla S, Poeta E, Monti B, Falkeis C, Vieth M, Hübner H, Gmeiner P, Maitra R, Maurice T, Decker M. Scheiner M, et al. Among authors: monti b. J Med Chem. 2019 Oct 24;62(20):9078-9102. doi: 10.1021/acs.jmedchem.9b00623. Epub 2019 Oct 14. J Med Chem. 2019. PMID: 31609608 Free PMC article.
Memory-enhancing drugs: a molecular perspective.
Monti B, Contestabile A. Monti B, et al. Mini Rev Med Chem. 2009 Jun;9(7):769-81. doi: 10.2174/138955709788452621. Mini Rev Med Chem. 2009. PMID: 19519502 Review.
Multitarget drug design strategy: quinone-tacrine hybrids designed to block amyloid-β aggregation and to exert anticholinesterase and antioxidant effects.
Nepovimova E, Uliassi E, Korabecny J, Peña-Altamira LE, Samez S, Pesaresi A, Garcia GE, Bartolini M, Andrisano V, Bergamini C, Fato R, Lamba D, Roberti M, Kuca K, Monti B, Bolognesi ML. Nepovimova E, et al. Among authors: monti b. J Med Chem. 2014 Oct 23;57(20):8576-89. doi: 10.1021/jm5010804. Epub 2014 Oct 10. J Med Chem. 2014. PMID: 25259726
Novel tacrine-grafted Ugi adducts as multipotent anti-Alzheimer drugs: a synthetic renewal in tacrine-ferulic acid hybrids.
Benchekroun M, Bartolini M, Egea J, Romero A, Soriano E, Pudlo M, Luzet V, Andrisano V, Jimeno ML, López MG, Wehle S, Gharbi T, Refouvelet B, de Andrés L, Herrera-Arozamena C, Monti B, Bolognesi ML, Rodríguez-Franco MI, Decker M, Marco-Contelles J, Ismaili L. Benchekroun M, et al. Among authors: monti b. ChemMedChem. 2015 Mar;10(3):523-39. doi: 10.1002/cmdc.201402409. Epub 2014 Dec 23. ChemMedChem. 2015. PMID: 25537267
Tacrine-resveratrol fused hybrids as multi-target-directed ligands against Alzheimer's disease.
Jeřábek J, Uliassi E, Guidotti L, Korábečný J, Soukup O, Sepsova V, Hrabinova M, Kuča K, Bartolini M, Peña-Altamira LE, Petralla S, Monti B, Roberti M, Bolognesi ML. Jeřábek J, et al. Among authors: monti b. Eur J Med Chem. 2017 Feb 15;127:250-262. doi: 10.1016/j.ejmech.2016.12.048. Epub 2016 Dec 26. Eur J Med Chem. 2017. PMID: 28064079
99 results