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TFPa/HADHA is required for fatty acid beta-oxidation and cardiolipin re-modeling in human cardiomyocytes.
Miklas JW, Clark E, Levy S, Detraux D, Leonard A, Beussman K, Showalter MR, Smith AT, Hofsteen P, Yang X, Macadangdang J, Manninen T, Raftery D, Madan A, Suomalainen A, Kim DH, Murry CE, Fiehn O, Sniadecki NJ, Wang Y, Ruohola-Baker H. Miklas JW, et al. Among authors: fiehn o. Nat Commun. 2019 Oct 11;10(1):4671. doi: 10.1038/s41467-019-12482-1. Nat Commun. 2019. PMID: 31604922 Free PMC article.
The metabolome regulates the epigenetic landscape during naive-to-primed human embryonic stem cell transition.
Sperber H, Mathieu J, Wang Y, Ferreccio A, Hesson J, Xu Z, Fischer KA, Devi A, Detraux D, Gu H, Battle SL, Showalter M, Valensisi C, Bielas JH, Ericson NG, Margaretha L, Robitaille AM, Margineantu D, Fiehn O, Hockenbery D, Blau CA, Raftery D, Margolin AA, Hawkins RD, Moon RT, Ware CB, Ruohola-Baker H. Sperber H, et al. Among authors: fiehn o. Nat Cell Biol. 2015 Dec;17(12):1523-35. doi: 10.1038/ncb3264. Epub 2015 Nov 16. Nat Cell Biol. 2015. PMID: 26571212 Free PMC article.
Epimetabolites: discovering metabolism beyond building and burning.
Showalter MR, Cajka T, Fiehn O. Showalter MR, et al. Among authors: fiehn o. Curr Opin Chem Biol. 2017 Feb;36:70-76. doi: 10.1016/j.cbpa.2017.01.012. Epub 2017 Feb 16. Curr Opin Chem Biol. 2017. PMID: 28213207 Free PMC article. Review.
Identification of small molecules using accurate mass MS/MS search.
Kind T, Tsugawa H, Cajka T, Ma Y, Lai Z, Mehta SS, Wohlgemuth G, Barupal DK, Showalter MR, Arita M, Fiehn O. Kind T, et al. Among authors: fiehn o. Mass Spectrom Rev. 2018 Jul;37(4):513-532. doi: 10.1002/mas.21535. Epub 2017 Apr 24. Mass Spectrom Rev. 2018. PMID: 28436590 Free PMC article. Review.
Obesogenic diets alter metabolism in mice.
Showalter MR, Nonnecke EB, Linderholm AL, Cajka T, Sa MR, Lönnerdal B, Kenyon NJ, Fiehn O. Showalter MR, et al. Among authors: fiehn o. PLoS One. 2018 Jan 11;13(1):e0190632. doi: 10.1371/journal.pone.0190632. eCollection 2018. PLoS One. 2018. PMID: 29324762 Free PMC article.
Salvage of the 5-deoxyribose byproduct of radical SAM enzymes.
Beaudoin GAW, Li Q, Folz J, Fiehn O, Goodsell JL, Angerhofer A, Bruner SD, Hanson AD. Beaudoin GAW, et al. Among authors: fiehn o. Nat Commun. 2018 Aug 6;9(1):3105. doi: 10.1038/s41467-018-05589-4. Nat Commun. 2018. PMID: 30082730 Free PMC article.
493 results