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Application of the adverse outcome pathway framework to genotoxic modes of action.
Sasaki JC, Allemang A, Bryce SM, Custer L, Dearfield KL, Dietz Y, Elhajouji A, Escobar PA, Fornace AJ Jr, Froetschl R, Galloway S, Hemmann U, Hendriks G, Li HH, Luijten M, Ouedraogo G, Peel L, Pfuhler S, Roberts DJ, Thybaud V, van Benthem J, Yauk CL, Schuler M. Sasaki JC, et al. Among authors: hemmann u. Environ Mol Mutagen. 2020 Jan;61(1):114-134. doi: 10.1002/em.22339. Epub 2019 Oct 31. Environ Mol Mutagen. 2020. PMID: 31603995
Interlaboratory evaluation of a multiplexed high information content in vitro genotoxicity assay.
Bryce SM, Bernacki DT, Bemis JC, Spellman RA, Engel ME, Schuler M, Lorge E, Heikkinen PT, Hemmann U, Thybaud V, Wilde S, Queisser N, Sutter A, Zeller A, Guérard M, Kirkland D, Dertinger SD. Bryce SM, et al. Among authors: hemmann u. Environ Mol Mutagen. 2017 Apr;58(3):146-161. doi: 10.1002/em.22083. Environ Mol Mutagen. 2017. PMID: 28370322 Free PMC article.
Analysis of historical negative control group data from the rat in vivo micronucleus assay.
Lovell DP, Fellows M, Saul J, Whitwell J, Custer L, Dertinger S, Escobar P, Fiedler R, Hemmann U, Kenny J, Smith R, van der Leede BM, Zeller A. Lovell DP, et al. Among authors: hemmann u. Mutat Res Genet Toxicol Environ Mutagen. 2020 Jan;849:503086. doi: 10.1016/j.mrgentox.2019.503086. Epub 2019 Oct 12. Mutat Res Genet Toxicol Environ Mutagen. 2020. PMID: 32087845
Fate of micronuclei and micronucleated cells.
Hintzsche H, Hemmann U, Poth A, Utesch D, Lott J, Stopper H; Working Group “In vitro micronucleus test”, Gesellschaft für Umwelt-Mutationsforschung (GUM, German-speaking section of the European Environmental Mutagenesis and Genomics Society EEMGS). Hintzsche H, et al. Among authors: hemmann u. Mutat Res Rev Mutat Res. 2017 Jan-Mar;771:85-98. doi: 10.1016/j.mrrev.2017.02.002. Epub 2017 Feb 13. Mutat Res Rev Mutat Res. 2017. PMID: 28342454 Review.
Liver-Specific Knockdown of Class IIa HDACs Has Limited Efficacy on Glucose Metabolism but Entails Severe Organ Side Effects in Mice.
Ziegler N, Raichur S, Brunner B, Hemmann U, Stolte M, Schwahn U, Prochnow HP, Metz-Weidmann C, Tennagels N, Margerie D, Wohlfart P, Bielohuby M. Ziegler N, et al. Among authors: hemmann u. Front Endocrinol (Lausanne). 2020 Aug 28;11:598. doi: 10.3389/fendo.2020.00598. eCollection 2020. Front Endocrinol (Lausanne). 2020. PMID: 32982982 Free PMC article.
A highly selective telomerase inhibitor limiting human cancer cell proliferation.
Damm K, Hemmann U, Garin-Chesa P, Hauel N, Kauffmann I, Priepke H, Niestroj C, Daiber C, Enenkel B, Guilliard B, Lauritsch I, Müller E, Pascolo E, Sauter G, Pantic M, Martens UM, Wenz C, Lingner J, Kraut N, Rettig WJ, Schnapp A. Damm K, et al. Among authors: hemmann u. EMBO J. 2001 Dec 17;20(24):6958-68. doi: 10.1093/emboj/20.24.6958. EMBO J. 2001. PMID: 11742973 Free PMC article.
Full Profiling of GE81112A, an Underexplored Tetrapeptide Antibiotic with Activity against Gram-Negative Pathogens.
Schuler SMM, Jürjens G, Marker A, Hemmann U, Rey A, Yvon S, Lagrevol M, Hamiti M, Nguyen F, Hirsch R, Pöverlein C, Vilcinskas A, Hammann P, Wilson DN, Mourez M, Coyne S, Bauer A. Schuler SMM, et al. Among authors: hemmann u. Microbiol Spectr. 2023 Jun 15;11(3):e0224722. doi: 10.1128/spectrum.02247-22. Epub 2023 May 4. Microbiol Spectr. 2023. PMID: 37140391 Free PMC article.
18 results