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Dual acting antioxidant A1 adenosine receptor agonists.
Gregg A, Bottle SE, Devine SM, Figler H, Linden J, White P, Pouton CW, Urmaliya V, Scammells PJ. Gregg A, et al. Among authors: scammells pj. Bioorg Med Chem Lett. 2007 Oct 1;17(19):5437-41. doi: 10.1016/j.bmcl.2007.07.035. Epub 2007 Jul 25. Bioorg Med Chem Lett. 2007. PMID: 17689079 Free article.
Determination of adenosine A1 receptor agonist and antagonist pharmacology using Saccharomyces cerevisiae: implications for ligand screening and functional selectivity.
Stewart GD, Valant C, Dowell SJ, Mijaljica D, Devenish RJ, Scammells PJ, Sexton PM, Christopoulos A. Stewart GD, et al. Among authors: scammells pj. J Pharmacol Exp Ther. 2009 Oct;331(1):277-86. doi: 10.1124/jpet.109.158667. Epub 2009 Jul 29. J Pharmacol Exp Ther. 2009. PMID: 19641164 Free PMC article.
A novel highly selective adenosine A1 receptor agonist VCP28 reduces ischemia injury in a cardiac cell line and ischemia-reperfusion injury in isolated rat hearts at concentrations that do not affect heart rate.
Urmaliya VB, Pouton CW, Devine SM, Haynes JM, Warfe L, Scammells PJ, White PJ. Urmaliya VB, et al. Among authors: scammells pj. J Cardiovasc Pharmacol. 2010 Sep;56(3):282-92. doi: 10.1097/FJC.0b013e3181eb8563. J Cardiovasc Pharmacol. 2010. PMID: 20571427
Novel adenosine A(2A) receptor ligands: a synthetic, functional and computational investigation of selected literature adenosine A(2A) receptor antagonists for extending into extracellular space.
Jörg M, Shonberg J, Mak FS, Miller ND, Yuriev E, Scammells PJ, Capuano B. Jörg M, et al. Among authors: scammells pj. Bioorg Med Chem Lett. 2013 Jun 1;23(11):3427-33. doi: 10.1016/j.bmcl.2013.03.070. Epub 2013 Apr 2. Bioorg Med Chem Lett. 2013. PMID: 23602401
158 results