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A novel, safe, fast and efficient treatment for Her2-positive and negative bladder cancer utilizing an EGF-anthrax toxin chimera.
Jack S, Madhivanan K, Ramadesikan S, Subramanian S, Edwards DF 2nd, Elzey BD, Dhawan D, McCluskey A, Kischuk EM, Loftis AR, Truex N, Santos M, Lu M, Rabideau A, Pentelute B, Collier J, Kaimakliotis H, Koch M, Ratliff TL, Knapp DW, Aguilar RC. Jack S, et al. Among authors: lu m. Int J Cancer. 2020 Jan 15;146(2):449-460. doi: 10.1002/ijc.32719. Epub 2019 Nov 1. Int J Cancer. 2020. PMID: 31584195 Free PMC article.
Anthrax toxins regulate pain signaling and can deliver molecular cargoes into ANTXR2+ DRG sensory neurons.
Yang NJ, Isensee J, Neel DV, Quadros AU, Zhang HB, Lauzadis J, Liu SM, Shiers S, Belu A, Palan S, Marlin S, Maignel J, Kennedy-Curran A, Tong VS, Moayeri M, Röderer P, Nitzsche A, Lu M, Pentelute BL, Brüstle O, Tripathi V, Foster KA, Price TJ, Collier RJ, Leppla SH, Puopolo M, Bean BP, Cunha TM, Hucho T, Chiu IM. Yang NJ, et al. Among authors: lu m. Nat Neurosci. 2022 Feb;25(2):168-179. doi: 10.1038/s41593-021-00973-8. Epub 2021 Dec 20. Nat Neurosci. 2022. PMID: 34931070 Free PMC article.
CD151-α3β1 integrin complexes are prognostic markers of glioblastoma and cooperate with EGFR to drive tumor cell motility and invasion.
Zhou P, Erfani S, Liu Z, Jia C, Chen Y, Xu B, Deng X, Alfáro JE, Chen L, Napier D, Lu M, Huang JA, Liu C, Thibault O, Segal R, Zhou BP, Kyprianou N, Horbinski C, Yang XH. Zhou P, et al. Among authors: lu m. Oncotarget. 2015 Oct 6;6(30):29675-93. doi: 10.18632/oncotarget.4896. Oncotarget. 2015. PMID: 26377974 Free PMC article.
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