Shearer JD - Search Results

1

GC-072: A Novel Therapeutic Candidate for Oral Treatment of Melioidosis and Infections Caused by Select Biothreat Pathogens.

Shearer JD, Saylor ML, Butler CM, Treston AM, Heine HS, Chirakul S, Schweizer HP, Louie A, Drusano GL, Zumbrun SD, Warfield KL. Shearer JD, et al. Antimicrob Agents Chemother. 2019 Sep 9;63(12):e00834-19. doi: 10.1128/AAC.00834-19. Epub 2019 Sep 23. Antimicrob Agents Chemother. 2019. PMID: 31548183 Free PMC article.

2

Reproductive and developmental toxicology studies of iminosugar UV-4.

Shearer J, Wolfe G, Khaliq M, Kaufman B, Sampath A, Warfield KL, Ramstedt U, Treston A. Shearer J, et al. Reprod Toxicol. 2022 Dec;114:9-21. doi: 10.1016/j.reprotox.2022.09.007. Epub 2022 Oct 4. Reprod Toxicol. 2022. PMID: 36206921 Free article.

3

Investigational New Drug Enabling Nonclinical Safety Assessment of the Iminosugar UV-4, a Broad-Spectrum Host-Targeted Antiviral Agent.

Shearer J, Wolfe G, Sampath A, Warfield KL, Kaufman B, Ramstedt U, Treston A. Shearer J, et al. Int J Toxicol. 2022 May-Jun;41(3):182-200. doi: 10.1177/10915818221077225. Epub 2022 Apr 15. Int J Toxicol. 2022. PMID: 35426748

4

Investigational New Drug Enabling Nonclinical Safety Pharmacology Assessment of the Iminosugar UV-4, a Broad-Spectrum Host-Targeted Antiviral Agent.

Shearer J, Wolfe G, Sampath A, Warfield KL, Kaufman B, Ramstedt U, Treston A. Shearer J, et al. Int J Toxicol. 2022 May-Jun;41(3):201-211. doi: 10.1177/10915818211072842. Epub 2022 Feb 28. Int J Toxicol. 2022. PMID: 35227115 Free PMC article.

5

Biological activity of an intravenous preparation of human vaccinia immune globulin in mouse models of vaccinia virus infection.

Shearer JD, Siemann L, Gerkovich M, House RV. Shearer JD, et al. Antimicrob Agents Chemother. 2005 Jul;49(7):2634-41. doi: 10.1128/AAC.49.7.2634-2641.2005. Antimicrob Agents Chemother. 2005. PMID: 15980330 Free PMC article.

6

Correlation between anthrax lethal toxin neutralizing antibody levels and survival in guinea pigs and nonhuman primates vaccinated with the AV7909 anthrax vaccine candidate.

Savransky V, Shearer JD, Gainey MR, Sanford DC, Sivko GS, Stark GV, Li N, Ionin B, Lacy MJ, Skiadopoulos MH. Savransky V, et al. Among authors: shearer jd. Vaccine. 2017 Sep 5;35(37):4952-4959. doi: 10.1016/j.vaccine.2017.07.076. Epub 2017 Jul 31. Vaccine. 2017. PMID: 28774566 Free PMC article.

7

Efficacy of the AV7909 anthrax vaccine candidate in guinea pigs and nonhuman primates following two immunizations two weeks apart.

Shearer JD, Henning L, Sanford DC, Li N, Skiadopoulos MH, Reece JJ, Ionin B, Savransky V. Shearer JD, et al. Vaccine. 2021 Jan 3;39(1):1-5. doi: 10.1016/j.vaccine.2020.10.095. Epub 2020 Nov 13. Vaccine. 2021. PMID: 33199078 Free article.

8

Development of a guinea pig inhalational anthrax model for evaluation of post-exposure prophylaxis efficacy of anthrax vaccines.

Perry MR, Ionin B, Barnewall RE, Vassar ML, Reece JJ, Park S, Lemiale L, Skiadopoulos MH, Shearer JD, Savransky V. Perry MR, et al. Among authors: shearer jd. Vaccine. 2020 Feb 28;38(10):2307-2314. doi: 10.1016/j.vaccine.2020.01.068. Epub 2020 Feb 3. Vaccine. 2020. PMID: 32029323 Free PMC article.

9

Repeat Dose Toxicity Study of the AV7909 Anthrax Vaccine Candidate in Juvenile Rats.

Zmarowski A, Ballin JD, Sharits J, Carrico K, Novak J, Shearer J, Blauth B, Ionin B, Reece J, Savransky V. Zmarowski A, et al. Among authors: shearer j. Int J Toxicol. 2020 Jul 21:1091581820941412. doi: 10.1177/1091581820941412. Online ahead of print. Int J Toxicol. 2020. PMID: 32691648

10

Developmental and reproductive safety evaluation of AV7909 anthrax vaccine candidate in rats.

Mylchreest E, Smiley MA, Ballin JD, Blauth B, Shearer J, Reece J, Ionin B, Savransky V. Mylchreest E, et al. Among authors: shearer j. Birth Defects Res. 2021 Jan 1;113(1):32-42. doi: 10.1002/bdr2.1815. Epub 2020 Oct 16. Birth Defects Res. 2021. PMID: 33067910 Free PMC article.

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