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Fragment-based discovery of the first nonpeptidyl inhibitor of an S46 family peptidase.
Sakamoto Y, Suzuki Y, Nakamura A, Watanabe Y, Sekiya M, Roppongi S, Kushibiki C, Iizuka I, Tani O, Sakashita H, Inaka K, Tanaka H, Yamada M, Ohta K, Honma N, Shida Y, Ogasawara W, Nakanishi-Matsui M, Nonaka T, Gouda H, Tanaka N. Sakamoto Y, et al. Among authors: sekiya m. Sci Rep. 2019 Sep 19;9(1):13587. doi: 10.1038/s41598-019-49984-3. Sci Rep. 2019. PMID: 31537874 Free PMC article.
Role of α/β interface in F1 ATPase rotational catalysis probed by inhibitors and mutations.
Sekiya M, Sakamoto Y, Futai M, Nakanishi-Matsui M. Sekiya M, et al. Int J Biol Macromol. 2017 Jun;99:615-621. doi: 10.1016/j.ijbiomac.2017.02.089. Epub 2017 Feb 27. Int J Biol Macromol. 2017. PMID: 28246051
Phytopolyphenols such as curcumin can inhibit bulk phase F(1) ATPase activity by extending the catalytic dwell time during subunit rotation (Sekiya, M., Hisasaka, R., Iwamoto-Kihara, A., Futai, M., Nakanishi-Matsui, M., Biochem. ...
Phytopolyphenols such as curcumin can inhibit bulk phase F(1) ATPase activity by extending the catalytic dwell time during subunit rotation …
A unique mechanism of curcumin inhibition on F1 ATPase.
Sekiya M, Hisasaka R, Iwamoto-Kihara A, Futai M, Nakanishi-Matsui M. Sekiya M, et al. Biochem Biophys Res Commun. 2014 Oct 3;452(4):940-4. doi: 10.1016/j.bbrc.2014.09.027. Epub 2014 Sep 16. Biochem Biophys Res Commun. 2014. PMID: 25230139
467 results