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Exenatide regulates pancreatic islet integrity and insulin sensitivity in the nonhuman primate baboon Papio hamadryas.
Fiorentino TV, Casiraghi F, Davalli AM, Finzi G, La Rosa S, Higgins PB, Abrahamian GA, Marando A, Sessa F, Perego C, Guardado-Mendoza R, Kamath S, Ricotti A, Fiorina P, Daniele G, Paez AM, Andreozzi F, Bastarrachea RA, Comuzzie AG, Gastaldelli A, Chavez AO, Di Cairano ES, Frost P, Luzi L, Dick EJ, Halff GA, DeFronzo RA, Folli F. Fiorentino TV, et al. Among authors: comuzzie ag. JCI Insight. 2019 Oct 17;4(20):e93091. doi: 10.1172/jci.insight.93091. JCI Insight. 2019. PMID: 31536476 Free PMC article.
Pancreatic islet amyloidosis, beta-cell apoptosis, and alpha-cell proliferation are determinants of islet remodeling in type-2 diabetic baboons.
Guardado-Mendoza R, Davalli AM, Chavez AO, Hubbard GB, Dick EJ, Majluf-Cruz A, Tene-Perez CE, Goldschmidt L, Hart J, Perego C, Comuzzie AG, Tejero ME, Finzi G, Placidi C, La Rosa S, Capella C, Halff G, Gastaldelli A, DeFronzo RA, Folli F. Guardado-Mendoza R, et al. Among authors: comuzzie ag. Proc Natl Acad Sci U S A. 2009 Aug 18;106(33):13992-7. doi: 10.1073/pnas.0906471106. Epub 2009 Jul 30. Proc Natl Acad Sci U S A. 2009. PMID: 19666551 Free PMC article.
Chronic continuous exenatide infusion does not cause pancreatic inflammation and ductal hyperplasia in non-human primates.
Fiorentino TV, Owston M, Abrahamian G, La Rosa S, Marando A, Perego C, Di Cairano ES, Finzi G, Capella C, Sessa F, Casiraghi F, Paez A, Adivi A, Davalli A, Fiorina P, Guardado Mendoza R, Comuzzie AG, Sharp M, DeFronzo RA, Halff G, Dick EJ, Folli F. Fiorentino TV, et al. Among authors: comuzzie ag. Am J Pathol. 2015 Jan;185(1):139-50. doi: 10.1016/j.ajpath.2014.09.009. Epub 2014 Nov 6. Am J Pathol. 2015. PMID: 25447052 Free PMC article.
Physiological and molecular determinants of insulin action in the baboon.
Chavez AO, Lopez-Alvarenga JC, Tejero ME, Triplitt C, Bastarrachea RA, Sriwijitkamol A, Tantiwong P, Voruganti VS, Musi N, Comuzzie AG, DeFronzo RA, Folli F. Chavez AO, et al. Among authors: comuzzie ag. Diabetes. 2008 Apr;57(4):899-908. doi: 10.2337/db07-0790. Epub 2008 Jan 3. Diabetes. 2008. PMID: 18174524
Predictive models of insulin resistance derived from simple morphometric and biochemical indices related to obesity and the metabolic syndrome in baboons.
Chavez AO, Gastaldelli A, Guardado-Mendoza R, Lopez-Alvarenga JC, Leland MM, Tejero ME, Sorice G, Casiraghi F, Davalli A, Bastarrachea RA, Comuzzie AG, DeFronzo RA, Folli F. Chavez AO, et al. Among authors: comuzzie ag. Cardiovasc Diabetol. 2009 Apr 23;8:22. doi: 10.1186/1475-2840-8-22. Cardiovasc Diabetol. 2009. PMID: 19389241 Free PMC article.
Coordinated defects in hepatic long chain fatty acid metabolism and triglyceride accumulation contribute to insulin resistance in non-human primates.
Kamath S, Chavez AO, Gastaldelli A, Casiraghi F, Halff GA, Abrahamian GA, Davalli AM, Bastarrachea RA, Comuzzie AG, Guardado-Mendoza R, Jimenez-Ceja LM, Mattern V, Paez AM, Ricotti A, Tejero ME, Higgins PB, Rodriguez-Sanchez IP, Tripathy D, DeFronzo RA, Dick EJ Jr, Cline GW, Folli F. Kamath S, et al. Among authors: comuzzie ag. PLoS One. 2011;6(11):e27617. doi: 10.1371/journal.pone.0027617. Epub 2011 Nov 18. PLoS One. 2011. PMID: 22125617 Free PMC article.
Successful β cells islet regeneration in streptozotocin-induced diabetic baboons using ultrasound-targeted microbubble gene therapy with cyclinD2/CDK4/GLP1.
Chen S, Bastarrachea RA, Roberts BJ, Voruganti VS, Frost PA, Nava-Gonzalez EJ, Arriaga-Cazares HE, Chen J, Huang P, DeFronzo RA, Comuzzie AG, Grayburn PA. Chen S, et al. Among authors: comuzzie ag. Cell Cycle. 2014;13(7):1145-51. doi: 10.4161/cc.27997. Epub 2014 Feb 10. Cell Cycle. 2014. PMID: 24553120 Free PMC article.
Successful pharmaceutical-grade streptozotocin (STZ)-induced hyperglycemia in a conscious tethered baboon (Papio hamadryas) model.
Frost PA, Chen S, Mezzles MJ, Voruganti VS, Nava-Gonzalez EJ, Arriaga-Cazares HE, Freed KA, Comuzzie AG, DeFronzo RA, Kent JW Jr, Grayburn PA, Bastarrachea RA. Frost PA, et al. Among authors: comuzzie ag. J Med Primatol. 2015 Aug;44(4):202-17. doi: 10.1111/jmp.12182. Epub 2015 Jun 30. J Med Primatol. 2015. PMID: 26122701 Free PMC article.
Central GIP signaling stimulates peripheral GIP release and promotes insulin and pancreatic polypeptide secretion in nonhuman primates.
Higgins PB, Shade RE, Rodríguez-Sánchez IP, Garcia-Forey M, Tejero ME, Voruganti VS, Cole SA, Comuzzie AG, Folli F. Higgins PB, et al. Among authors: comuzzie ag. Am J Physiol Endocrinol Metab. 2016 Oct 1;311(4):E661-E670. doi: 10.1152/ajpendo.00166.2016. Epub 2016 Aug 16. Am J Physiol Endocrinol Metab. 2016. PMID: 27530231 Free PMC article.
296 results