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Atp6ap2 deletion causes extensive vacuolation that consumes the insulin content of pancreatic β cells.
Binger KJ, Neukam M, Tattikota SG, Qadri F, Puchkov D, Willmes DM, Wurmsee S, Geisberger S, Dechend R, Raile K, Kurth T, Nguyen G, Poy MN, Solimena M, Muller DN, Birkenfeld AL. Binger KJ, et al. Among authors: willmes dm. Proc Natl Acad Sci U S A. 2019 Oct 1;116(40):19983-19988. doi: 10.1073/pnas.1903678116. Epub 2019 Sep 16. Proc Natl Acad Sci U S A. 2019. PMID: 31527264 Free PMC article.
The Role of INDY in Metabolic Regulation.
Willmes DM, Birkenfeld AL. Willmes DM, et al. Comput Struct Biotechnol J. 2013 Dec 8;6:e201303020. doi: 10.5936/csbj.201303020. eCollection 2013. Comput Struct Biotechnol J. 2013. PMID: 24688728 Free PMC article. Review.
Prevention of diet-induced hepatic steatosis and hepatic insulin resistance by second generation antisense oligonucleotides targeted to the longevity gene mIndy (Slc13a5).
Pesta DH, Perry RJ, Guebre-Egziabher F, Zhang D, Jurczak M, Fischer-Rosinsky A, Daniels MA, Willmes DM, Bhanot S, Bornstein SR, Knauf F, Samuel VT, Shulman GI, Birkenfeld AL. Pesta DH, et al. Among authors: willmes dm. Aging (Albany NY). 2015 Dec;7(12):1086-93. doi: 10.18632/aging.100854. Aging (Albany NY). 2015. PMID: 26647160 Free PMC article.
Deletion of the diabetes candidate gene Slc16a13 in mice attenuates diet-induced ectopic lipid accumulation and insulin resistance.
Schumann T, König J, von Loeffelholz C, Vatner DF, Zhang D, Perry RJ, Bernier M, Chami J, Henke C, Kurzbach A, El-Agroudy NN, Willmes DM, Pesta D, de Cabo R, O Sullivan JF, Simon E, Shulman GI, Hamilton BS, Birkenfeld AL. Schumann T, et al. Among authors: willmes dm. Commun Biol. 2021 Jul 1;4(1):826. doi: 10.1038/s42003-021-02279-8. Commun Biol. 2021. PMID: 34211098 Free PMC article.
The longevity gene mIndy (I'm Not Dead, Yet) affects blood pressure through sympathoadrenal mechanisms.
Willmes DM, Daniels M, Kurzbach A, Lieske S, Bechmann N, Schumann T, Henke C, El-Agroudy NN, Da Costa Goncalves AC, Peitzsch M, Hofmann A, Kanczkowski W, Kräker K, Müller DN, Morawietz H, Deussen A, Wagner M, El-Armouche A, Helfand SL, Bornstein SR, de Cabo R, Bernier M, Eisenhofer G, Tank J, Jordan J, Birkenfeld AL. Willmes DM, et al. JCI Insight. 2021 Jan 25;6(2):e136083. doi: 10.1172/jci.insight.136083. JCI Insight. 2021. PMID: 33491666 Free PMC article.
21 results