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Atp6ap2 deletion causes extensive vacuolation that consumes the insulin content of pancreatic β cells.
Binger KJ, Neukam M, Tattikota SG, Qadri F, Puchkov D, Willmes DM, Wurmsee S, Geisberger S, Dechend R, Raile K, Kurth T, Nguyen G, Poy MN, Solimena M, Muller DN, Birkenfeld AL. Binger KJ, et al. Among authors: solimena m. Proc Natl Acad Sci U S A. 2019 Oct 1;116(40):19983-19988. doi: 10.1073/pnas.1903678116. Epub 2019 Sep 16. Proc Natl Acad Sci U S A. 2019. PMID: 31527264 Free PMC article.
Sequential in vivo labeling of insulin secretory granule pools in INS-SNAP transgenic pigs.
Kemter E, Müller A, Neukam M, Ivanova A, Klymiuk N, Renner S, Yang K, Broichhagen J, Kurome M, Zakhartchenko V, Kessler B, Knoch KP, Bickle M, Ludwig B, Johnsson K, Lickert H, Kurth T, Wolf E, Solimena M. Kemter E, et al. Among authors: solimena m. Proc Natl Acad Sci U S A. 2021 Sep 14;118(37):e2107665118. doi: 10.1073/pnas.2107665118. Proc Natl Acad Sci U S A. 2021. PMID: 34508004 Free PMC article.
A 4D view on insulin secretory granule turnover in the β-cell.
Müller A, Mziaut H, Neukam M, Knoch KP, Solimena M. Müller A, et al. Among authors: solimena m. Diabetes Obes Metab. 2017 Sep;19 Suppl 1:107-114. doi: 10.1111/dom.13015. Diabetes Obes Metab. 2017. PMID: 28880479 Review.
Age-dependent labeling and imaging of insulin secretory granules.
Ivanova A, Kalaidzidis Y, Dirkx R, Sarov M, Gerlach M, Schroth-Diez B, Müller A, Liu Y, Andree C, Mulligan B, Münster C, Kurth T, Bickle M, Speier S, Anastassiadis K, Solimena M. Ivanova A, et al. Among authors: solimena m. Diabetes. 2013 Nov;62(11):3687-96. doi: 10.2337/db12-1819. Epub 2013 Aug 8. Diabetes. 2013. PMID: 23929935 Free PMC article.
Metabolic implications of pancreatic fat accumulation.
Wagner R, Eckstein SS, Yamazaki H, Gerst F, Machann J, Jaghutriz BA, Schürmann A, Solimena M, Singer S, Königsrainer A, Birkenfeld AL, Häring HU, Fritsche A, Ullrich S, Heni M. Wagner R, et al. Among authors: solimena m. Nat Rev Endocrinol. 2022 Jan;18(1):43-54. doi: 10.1038/s41574-021-00573-3. Epub 2021 Oct 20. Nat Rev Endocrinol. 2022. PMID: 34671102 Review.
Aged insulin granules display reduced microtubule-dependent mobility and are disposed within actin-positive multigranular bodies.
Hoboth P, Müller A, Ivanova A, Mziaut H, Dehghany J, Sönmez A, Lachnit M, Meyer-Hermann M, Kalaidzidis Y, Solimena M. Hoboth P, et al. Among authors: solimena m. Proc Natl Acad Sci U S A. 2015 Feb 17;112(7):E667-76. doi: 10.1073/pnas.1409542112. Epub 2015 Feb 2. Proc Natl Acad Sci U S A. 2015. PMID: 25646459 Free PMC article.
Creating a "Transcampus" in diabetes research between King's College London and the Technische Universität Dresden: update on islet biology and transplantation.
Bornstein SR, Amiel SA, Rubino F, Mingrone G, Kamvissi V, Solimena M, Bonifacio E, Jones P, Schwarz P, Birkenfeld AL, Behrens A, Barthel A, Lechler R, Peakman M. Bornstein SR, et al. Among authors: solimena m. Horm Metab Res. 2015 Jan;47(1):1-3. doi: 10.1055/s-0034-1394453. Epub 2014 Dec 5. Horm Metab Res. 2015. PMID: 25478704 No abstract available.
168 results