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Atp6ap2 deletion causes extensive vacuolation that consumes the insulin content of pancreatic β cells.
Binger KJ, Neukam M, Tattikota SG, Qadri F, Puchkov D, Willmes DM, Wurmsee S, Geisberger S, Dechend R, Raile K, Kurth T, Nguyen G, Poy MN, Solimena M, Muller DN, Birkenfeld AL. Binger KJ, et al. Among authors: birkenfeld al. Proc Natl Acad Sci U S A. 2019 Oct 1;116(40):19983-19988. doi: 10.1073/pnas.1903678116. Epub 2019 Sep 16. Proc Natl Acad Sci U S A. 2019. PMID: 31527264 Free PMC article.
The mammalian INDY homolog is induced by CREB in a rat model of type 2 diabetes.
Neuschäfer-Rube F, Lieske S, Kuna M, Henkel J, Perry RJ, Erion DM, Pesta D, Willmes DM, Brachs S, von Loeffelholz C, Tolkachov A, Schupp M, Pathe-Neuschäfer-Rube A, Pfeiffer AF, Shulman GI, Püschel GP, Birkenfeld AL. Neuschäfer-Rube F, et al. Among authors: birkenfeld al. Diabetes. 2014 Mar;63(3):1048-57. doi: 10.2337/db13-0749. Epub 2013 Nov 12. Diabetes. 2014. PMID: 24222346 Free PMC article.
The Role of INDY in Metabolic Regulation.
Willmes DM, Birkenfeld AL. Willmes DM, et al. Among authors: birkenfeld al. Comput Struct Biotechnol J. 2013 Dec 8;6:e201303020. doi: 10.5936/csbj.201303020. eCollection 2013. Comput Struct Biotechnol J. 2013. PMID: 24688728 Free PMC article. Review.
Creating a "Transcampus" in diabetes research between King's College London and the Technische Universität Dresden: update on islet biology and transplantation.
Bornstein SR, Amiel SA, Rubino F, Mingrone G, Kamvissi V, Solimena M, Bonifacio E, Jones P, Schwarz P, Birkenfeld AL, Behrens A, Barthel A, Lechler R, Peakman M. Bornstein SR, et al. Among authors: birkenfeld al. Horm Metab Res. 2015 Jan;47(1):1-3. doi: 10.1055/s-0034-1394453. Epub 2014 Dec 5. Horm Metab Res. 2015. PMID: 25478704 No abstract available.
Prevention of diet-induced hepatic steatosis and hepatic insulin resistance by second generation antisense oligonucleotides targeted to the longevity gene mIndy (Slc13a5).
Pesta DH, Perry RJ, Guebre-Egziabher F, Zhang D, Jurczak M, Fischer-Rosinsky A, Daniels MA, Willmes DM, Bhanot S, Bornstein SR, Knauf F, Samuel VT, Shulman GI, Birkenfeld AL. Pesta DH, et al. Among authors: birkenfeld al. Aging (Albany NY). 2015 Dec;7(12):1086-93. doi: 10.18632/aging.100854. Aging (Albany NY). 2015. PMID: 26647160 Free PMC article.
Pharmacogenomics in type 2 diabetes: oral antidiabetic drugs.
Daniels MA, Kan C, Willmes DM, Ismail K, Pistrosch F, Hopkins D, Mingrone G, Bornstein SR, Birkenfeld AL. Daniels MA, et al. Among authors: birkenfeld al. Pharmacogenomics J. 2016 Oct;16(5):399-410. doi: 10.1038/tpj.2016.54. Epub 2016 Jul 19. Pharmacogenomics J. 2016. PMID: 27432533 Review.
The human longevity gene homolog INDY and interleukin-6 interact in hepatic lipid metabolism.
von Loeffelholz C, Lieske S, Neuschäfer-Rube F, Willmes DM, Raschzok N, Sauer IM, König J, Fromm MF, Horn P, Chatzigeorgiou A, Pathe-Neuschäfer-Rube A, Jordan J, Pfeiffer AFH, Mingrone G, Bornstein SR, Stroehle P, Harms C, Wunderlich FT, Helfand SL, Bernier M, de Cabo R, Shulman GI, Chavakis T, Püschel GP, Birkenfeld AL. von Loeffelholz C, et al. Among authors: birkenfeld al. Hepatology. 2017 Aug;66(2):616-630. doi: 10.1002/hep.29089. Epub 2017 Jun 26. Hepatology. 2017. PMID: 28133767 Free PMC article.
278 results