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RIG-I activation is critical for responsiveness to checkpoint blockade.
Sci Immunol. 2019 Sep 13;4(39):eaau8943. doi: 10.1126/sciimmunol.aau8943.
Sci Immunol. 2019.
PMID: 31519811
RIG-I/MAVS and STING signaling promote gut integrity during irradiation- and immune-mediated tissue injury.
Fischer JC, Bscheider M, Eisenkolb G, Lin CC, Wintges A, Otten V, Lindemans CA, Heidegger S, Rudelius M, Monette S, Porosnicu Rodriguez KA, Calafiore M, Liebermann S, Liu C, Lienenklaus S, Weiss S, Kalinke U, Ruland J, Peschel C, Shono Y, Docampo M, Velardi E, Jenq RR, Hanash AM, Dudakov JA, Haas T, van den Brink MRM, Poeck H.
Fischer JC, et al. Among authors: wintges a.
Sci Transl Med. 2017 Apr 19;9(386):eaag2513. doi: 10.1126/scitranslmed.aag2513.
Sci Transl Med. 2017.
PMID: 28424327
Free PMC article.
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RIG-I activating immunostimulatory RNA boosts the efficacy of anticancer vaccines and synergizes with immune checkpoint blockade.
Heidegger S, Kreppel D, Bscheider M, Stritzke F, Nedelko T, Wintges A, Bek S, Fischer JC, Graalmann T, Kalinke U, Bassermann F, Haas T, Poeck H.
Heidegger S, et al. Among authors: wintges a.
EBioMedicine. 2019 Mar;41:146-155. doi: 10.1016/j.ebiom.2019.02.056. Epub 2019 Mar 6.
EBioMedicine. 2019.
PMID: 30852164
Free PMC article.
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Tumor cell-intrinsic RIG-I signaling governs synergistic effects of immunogenic cancer therapies and checkpoint inhibitors in mice.
Poeck H, Wintges A, Dahl S, Bassermann F, Haas T, Heidegger S.
Poeck H, et al. Among authors: wintges a.
Eur J Immunol. 2021 Jun;51(6):1531-1534. doi: 10.1002/eji.202049158. Epub 2021 Apr 5.
Eur J Immunol. 2021.
PMID: 33733474
Free article.
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Card9 controls Dectin-1-induced T-cell cytotoxicity and tumor growth in mice.
Haas T, Heidegger S, Wintges A, Bscheider M, Bek S, Fischer JC, Eisenkolb G, Schmickl M, Spoerl S, Peschel C, Poeck H, Ruland J.
Haas T, et al. Among authors: wintges a.
Eur J Immunol. 2017 May;47(5):872-879. doi: 10.1002/eji.201646775. Epub 2017 Apr 10.
Eur J Immunol. 2017.
PMID: 28295265
Free PMC article.
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Assessment of mucosal integrity by quantifying neutrophil granulocyte influx in murine models of acute intestinal injury.
Fischer JC, Wintges A, Haas T, Poeck H.
Fischer JC, et al. Among authors: wintges a.
Cell Immunol. 2017 Jun;316:70-76. doi: 10.1016/j.cellimm.2017.04.003. Epub 2017 Apr 11.
Cell Immunol. 2017.
PMID: 28413062
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Targeting intrinsic RIG-I signaling turns melanoma cells into type I interferon-releasing cellular antitumor vaccines.
Bek S, Stritzke F, Wintges A, Nedelko T, Böhmer DFR, Fischer JC, Haas T, Poeck H, Heidegger S.
Bek S, et al. Among authors: wintges a.
Oncoimmunology. 2019 Feb 11;8(4):e1570779. doi: 10.1080/2162402X.2019.1570779. eCollection 2019.
Oncoimmunology. 2019.
PMID: 30906666
Free PMC article.
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Regeneration After Radiation- and Immune-Mediated Tissue Injury Is Not Enhanced by Type III Interferon Signaling.
Fischer JC, Lin CC, Heidegger S, Wintges A, Schlapschy M, Beudert M, Combs SE, Bassermann F, Skerra A, Haas T, Poeck H.
Fischer JC, et al. Among authors: wintges a.
Int J Radiat Oncol Biol Phys. 2019 Mar 15;103(4):970-976. doi: 10.1016/j.ijrobp.2018.11.038. Epub 2018 Nov 29.
Int J Radiat Oncol Biol Phys. 2019.
PMID: 30503785
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