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Preclinical evaluation of topically-administered PEGylated Fab' lung toxicity.
Int J Pharm X. 2019 Jun 21;1:100019. doi: 10.1016/j.ijpx.2019.100019. eCollection 2019 Dec.
Int J Pharm X. 2019.
PMID: 31517284
Free PMC article.
PEGylation prolongs the pulmonary retention of an anti-IL-17A Fab' antibody fragment after pulmonary delivery in three different species.
Freches D, Patil HP, Machado Franco M, Uyttenhove C, Heywood S, Vanbever R.
Freches D, et al.
Int J Pharm. 2017 Apr 15;521(1-2):120-129. doi: 10.1016/j.ijpharm.2017.02.021. Epub 2017 Feb 10.
Int J Pharm. 2017.
PMID: 28192159
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Fate of PEGylated antibody fragments following delivery to the lungs: Influence of delivery site, PEG size and lung inflammation.
Patil HP, Freches D, Karmani L, Duncan GA, Ucakar B, Suk JS, Hanes J, Gallez B, Vanbever R.
Patil HP, et al. Among authors: freches d.
J Control Release. 2018 Feb 28;272:62-71. doi: 10.1016/j.jconrel.2017.12.009. Epub 2017 Dec 13.
J Control Release. 2018.
PMID: 29247664
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Increased pulmonary tumor necrosis factor alpha, interleukin-6 (IL-6), and IL-17A responses compensate for decreased gamma interferon production in anti-IL-12 autovaccine-treated, Mycobacterium bovis BCG-vaccinated mice.
Freches D, Romano M, Korf H, Renauld JC, Van Snick J, Uyttenhove C, Huygen K.
Freches D, et al.
Clin Vaccine Immunol. 2011 Jan;18(1):95-104. doi: 10.1128/CVI.00352-10. Epub 2010 Nov 17.
Clin Vaccine Immunol. 2011.
PMID: 21084465
Free PMC article.
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Mice genetically inactivated in interleukin-17A receptor are defective in long-term control of Mycobacterium tuberculosis infection.
Freches D, Korf H, Denis O, Havaux X, Huygen K, Romano M.
Freches D, et al.
Immunology. 2013 Oct;140(2):220-31. doi: 10.1111/imm.12130.
Immunology. 2013.
PMID: 23721367
Free PMC article.
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Role of B cells in host defense against primary Coxiella burnetii infection.
Schoenlaub L, Elliott A, Freches D, Mitchell WJ, Zhang G.
Schoenlaub L, et al. Among authors: freches d.
Infect Immun. 2015 Dec;83(12):4826-36. doi: 10.1128/IAI.01073-15. Epub 2015 Oct 5.
Infect Immun. 2015.
PMID: 26438792
Free PMC article.
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Neutrophils play an important role in protective immunity against Coxiella burnetii infection.
Elliott A, Schoenlaub L, Freches D, Mitchell W, Zhang G.
Elliott A, et al. Among authors: freches d.
Infect Immun. 2015 Aug;83(8):3104-13. doi: 10.1128/IAI.00042-15. Epub 2015 May 26.
Infect Immun. 2015.
PMID: 26015476
Free PMC article.
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