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Chronic Hypoxia Decreases Endothelial Connexin 40, Attenuates Endothelium-Dependent Hyperpolarization-Mediated Relaxation in Small Distal Pulmonary Arteries, and Leads to Pulmonary Hypertension.
Si R, Zhang Q, Cabrera JTO, Zheng Q, Tsuji-Hosokawa A, Watanabe M, Hosokawa S, Xiong M, Jain PP, Ashton AW, Yuan JX, Wang J, Makino A. Si R, et al. Among authors: yuan jx. J Am Heart Assoc. 2020 Dec 15;9(24):e018327. doi: 10.1161/JAHA.120.018327. Epub 2020 Dec 12. J Am Heart Assoc. 2020. PMID: 33307937 Free PMC article.
Halofuginone, a promising drug for treatment of pulmonary hypertension.
Jain PP, Zhao T, Xiong M, Song S, Lai N, Zheng Q, Chen J, Carr SG, Babicheva A, Izadi A, Rodriguez M, Rahimi S, Balistrieri F, Rahimi S, Simonson T, Valdez-Jasso D, Thistlethwaite PA, Shyy JY, Wang J, Makino A, Yuan JX. Jain PP, et al. Among authors: yuan jx. Br J Pharmacol. 2021 Sep;178(17):3373-3394. doi: 10.1111/bph.15442. Epub 2021 Jul 31. Br J Pharmacol. 2021. PMID: 33694155 Free PMC article.
HuR/Cx40 downregulation causes coronary microvascular dysfunction in type 2 diabetes.
Si R, Cabrera JTO, Tsuji-Hosokawa A, Guo R, Watanabe M, Gao L, Lee YS, Moon JS, Scott BT, Wang J, Ashton AW, Rao JN, Wang JY, Yuan JX, Makino A. Si R, et al. Among authors: yuan jx. JCI Insight. 2021 Nov 8;6(21):e147982. doi: 10.1172/jci.insight.147982. JCI Insight. 2021. PMID: 34747371 Free PMC article.
Tetramethylpyrazine: A promising drug for the treatment of pulmonary hypertension.
Chen Y, Lu W, Yang K, Duan X, Li M, Chen X, Zhang J, Kuang M, Liu S, Wu X, Zou G, Liu C, Hong C, He W, Liao J, Hou C, Zhang Z, Zheng Q, Chen J, Zhang N, Tang H, Vanderpool RR, Desai AA, Rischard F, Black SM, Garcia JGN, Makino A, Yuan JX, Zhong N, Wang J. Chen Y, et al. Among authors: yuan jx. Br J Pharmacol. 2020 Jun;177(12):2743-2764. doi: 10.1111/bph.15000. Epub 2020 Apr 27. Br J Pharmacol. 2020. PMID: 31976548 Free PMC article.
Divergent changes of p53 in pulmonary arterial endothelial and smooth muscle cells involved in the development of pulmonary hypertension.
Wang Z, Yang K, Zheng Q, Zhang C, Tang H, Babicheva A, Jiang Q, Li M, Chen Y, Carr SG, Wu K, Zhang Q, Balistrieri A, Wang C, Song S, Ayon RJ, Desai AA, Black SM, Garcia JGN, Makino A, Yuan JX, Lu W, Wang J. Wang Z, et al. Among authors: yuan jx. Am J Physiol Lung Cell Mol Physiol. 2019 Jan 1;316(1):L216-L228. doi: 10.1152/ajplung.00538.2017. Epub 2018 Oct 25. Am J Physiol Lung Cell Mol Physiol. 2019. PMID: 30358436 Free PMC article.
358 results