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LGR6 promotes osteogenesis by activating the Wnt/β-catenin signaling pathway.
Liu SL, Zhou YM, Tang DB, Zhou N, Zheng WW, Tang ZH, Duan CW, Zheng L, Chen J. Liu SL, et al. Among authors: zheng ww, zheng l. Biochem Biophys Res Commun. 2019 Oct 29;519(1):1-7. doi: 10.1016/j.bbrc.2019.08.122. Epub 2019 Sep 6. Biochem Biophys Res Commun. 2019. PMID: 31500806
AICAr suppresses cell proliferation by inducing NTP and dNTP pool imbalances in acute lymphoblastic leukemia cells.
Du L, Yang F, Fang H, Sun H, Chen Y, Xu Y, Li H, Zheng L, Zhou BS. Du L, et al. Among authors: zheng l. FASEB J. 2019 Mar;33(3):4525-4537. doi: 10.1096/fj.201801559RR. Epub 2019 Jan 31. FASEB J. 2019. PMID: 30702927
Our data indicate that RNA transcription inhibition and DNA replication stress induced by NTP and dNTP pool imbalances might play a key role in AICAr-mediated cytotoxic effects on ALL cells, suggesting a potential clinical application of AICAr in future ALL therapy.-Du, L. …
Our data indicate that RNA transcription inhibition and DNA replication stress induced by NTP and dNTP pool imbalances might play a key role …
Transketolase promotes MAFLD by limiting inosine-induced mitochondrial activity.
Tong L, Chen Z, Li Y, Wang X, Yang C, Li Y, Zhu Y, Lu Y, Liu Q, Xu N, Shao S, Wu L, Zhang P, Wu G, Wu X, Chen X, Fang J, Jia R, Xu T, Li B, Zheng L, Liu J, Tong X. Tong L, et al. Among authors: zheng l. Cell Metab. 2024 May 7;36(5):1013-1029.e5. doi: 10.1016/j.cmet.2024.03.003. Epub 2024 Mar 27. Cell Metab. 2024. PMID: 38547864
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