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Page 1
Prioritising the most needed paediatric antiretroviral formulations: the PADO4 list.
Penazzato M, Townsend CL, Rakhmanina N, Cheng Y, Archary M, Cressey TR, Kim MH, Musiime V, Turkova A, Ruel TD, Rabie H, Sugandhi N, Rojo P, Doherty M, Abrams EJ; PADO4 participants. Penazzato M, et al. Among authors: ruel td. Lancet HIV. 2019 Sep;6(9):e623-e631. doi: 10.1016/S2352-3018(19)30193-6. Lancet HIV. 2019. PMID: 31498110 Review.
Pharmacokinetics and safety of early nevirapine-based antiretroviral therapy for neonates at high risk for perinatal HIV infection: a phase 1/2 proof of concept study.
Ruel TD, Capparelli EV, Tierney C, Nelson BS, Coletti A, Bryson Y, Cotton MF, Spector SA, Mirochnick M, LeBlanc R, Reding C, Zimmer B, Persaud D, Bwakura-Dangarembizi M, Naidoo KL, Hazra R, Jean-Philippe P, Chadwick EG. Ruel TD, et al. Lancet HIV. 2021 Mar;8(3):e149-e157. doi: 10.1016/S2352-3018(20)30274-5. Epub 2020 Nov 23. Lancet HIV. 2021. PMID: 33242457 Free PMC article. Clinical Trial.
Adolescent participation in HIV research: consortium experience in low and middle-income countries and scoping review.
Day S, Kapogiannis BG, Shah SK, Wilson EC, Ruel TD, Conserve DF, Strode A, Donenberg GR, Kohler P, Slack C, Ezechi O, Tucker JD; PATC3H Consortium Adolescent Bioethics Working Group. Day S, et al. Among authors: ruel td. Lancet HIV. 2020 Dec;7(12):e844-e852. doi: 10.1016/S2352-3018(20)30269-1. Lancet HIV. 2020. PMID: 33275917 Free PMC article. Review.
Pharmacokinetics, safety, tolerability, and antiviral activity of dolutegravir dispersible tablets in infants and children with HIV-1 (IMPAACT P1093): results of an open-label, phase 1-2 trial.
Ruel TD, Acosta EP, Liu JP, Gray KP, George K, Montañez N, Popson S, Buchanan AM, Bartlett M, Dayton D, Anthony P, Brothers C, Vavro C, Singh R, Koech L, Vhembo T, Mmbaga BT, Pinto JA, Dobbels EFM, Archary M, Chokephaibulkit K, Ounchanum P, Deville JG, Hazra R, Townley E, Wiznia A; IMPAACT P1093 team. Ruel TD, et al. Lancet HIV. 2022 May;9(5):e332-e340. doi: 10.1016/S2352-3018(22)00044-3. Lancet HIV. 2022. PMID: 35489377 Free PMC article. Clinical Trial.
Advancing the prevention and treatment of HIV in children: priorities for research and development.
Penazzato M, Townsend CL, Sam-Agudu NA, Ruel TD, Archary M, Bekker A, Cressey TR, Colbers A, Sugandhi N, Rojo P, Rakhmanina N, Watkins M, Frigati L, Mukui I, Hafiz A, Vicari M, Capparelli EV, Abrams EJ; PADO-HIV 5 participants. Penazzato M, et al. Among authors: ruel td. Lancet HIV. 2022 Sep;9(9):e658-e666. doi: 10.1016/S2352-3018(22)00101-1. Epub 2022 Jul 18. Lancet HIV. 2022. PMID: 35863362 Review.
What babies need: accelerating access to current and novel antiretroviral drugs in neonates through pharmacokinetic studies.
Jacobs TG, Schouwenburg S, Penazzato M, Archary M, Ruel TD, van den Anker J, Burger DM, Cressey TR, Abrams EJ, Lyall H, Bekker A, Colbers A; Penta Clinical Pharmacology Working Group; PADO-HIV 5 participants. Jacobs TG, et al. Among authors: ruel td. Lancet HIV. 2022 Sep;9(9):e649-e657. doi: 10.1016/S2352-3018(22)00121-7. Epub 2022 Jul 18. Lancet HIV. 2022. PMID: 35863363 Review.
Hair and plasma data show that lopinavir, ritonavir, and efavirenz all transfer from mother to infant in utero, but only efavirenz transfers via breastfeeding.
Gandhi M, Mwesigwa J, Aweeka F, Plenty A, Charlebois E, Ruel TD, Huang Y, Clark T, Ades V, Natureeba P, Luwedde FA, Achan J, Kamya MR, Havlir DV, Cohan D; Prevention of Malaria and HIV disease in Tororo (PROMOTE) study. Gandhi M, et al. Among authors: ruel td. J Acquir Immune Defic Syndr. 2013 Aug 15;63(5):578-84. doi: 10.1097/QAI.0b013e31829c48ad. J Acquir Immune Defic Syndr. 2013. PMID: 24135775 Free PMC article. Clinical Trial.
Brief Report: Food Insufficiency Is Associated With Lack of Sustained Viral Suppression Among HIV-Infected Pregnant and Breastfeeding Ugandan Women.
Koss CA, Natureeba P, Nyafwono D, Plenty A, Mwesigwa J, Nzarubara B, Clark TD, Ruel TD, Achan J, Charlebois ED, Cohan D, Kamya MR, Havlir DV, Young SL. Koss CA, et al. Among authors: ruel td. J Acquir Immune Defic Syndr. 2016 Mar 1;71(3):310-5. doi: 10.1097/QAI.0000000000000860. J Acquir Immune Defic Syndr. 2016. PMID: 26397935 Free PMC article. Clinical Trial.
Antiretroviral Therapy With Efavirenz Accentuates Pregnancy-Associated Reduction of Dihydroartemisinin-Piperaquine Exposure During Malaria Chemoprevention.
Kajubi R, Huang L, Jagannathan P, Chamankhah N, Were M, Ruel T, Koss CA, Kakuru A, Mwebaza N, Kamya M, Havlir D, Dorsey G, Rosenthal PJ, Aweeka FT. Kajubi R, et al. Clin Pharmacol Ther. 2017 Sep;102(3):520-528. doi: 10.1002/cpt.664. Epub 2017 May 30. Clin Pharmacol Ther. 2017. PMID: 28187497 Free PMC article. Clinical Trial.
37 results