Qin L - Search Results

1

Structure-Based Discovery and Development of a Series of Potent and Selective Bromodomain and Extra-Terminal Protein Inhibitors.

Hu J, Tian CQ, Damaneh MS, Li Y, Cao D, Lv K, Yu T, Meng T, Chen D, Wang X, Chen L, Li J, Song SS, Huan XJ, Qin L, Shen J, Wang YQ, Miao ZH, Xiong B. Hu J, et al. Among authors: qin l. J Med Chem. 2019 Sep 26;62(18):8642-8663. doi: 10.1021/acs.jmedchem.9b01094. Epub 2019 Sep 16. J Med Chem. 2019. PMID: 31490070

2

Potent and Selective Mitogen-Activated Protein Kinase Kinase 1/2 (MEK1/2) Heterobifunctional Small-molecule Degraders.

Hu J, Wei J, Yim H, Wang L, Xie L, Jin MS, Kabir M, Qin L, Chen X, Liu J, Jin J. Hu J, et al. Among authors: qin l. J Med Chem. 2020 Dec 24;63(24):15883-15905. doi: 10.1021/acs.jmedchem.0c01609. Epub 2020 Dec 7. J Med Chem. 2020. PMID: 33284613 Free PMC article.

3

Multi-omics characterization of WNT pathway reactivation to ameliorate BET inhibitor resistance in liver cancer cells.

Liu Y, Xue M, Cao D, Qin L, Wang Y, Miao Z, Wang P, Hu X, Shen J, Xiong B. Liu Y, et al. Among authors: qin l. Genomics. 2021 May;113(3):1057-1069. doi: 10.1016/j.ygeno.2021.02.017. Epub 2021 Mar 2. Genomics. 2021. PMID: 33667649 Free article.

4

Discovery and Characterization of a Novel Cereblon-Recruiting PRC1 Bridged PROTAC Degrader.

Kabir M, Qin L, Luo K, Xiong Y, Sidi RA, Park KS, Jin J. Kabir M, et al. Among authors: qin l. J Med Chem. 2024 Apr 25;67(8):6880-6892. doi: 10.1021/acs.jmedchem.4c00538. Epub 2024 Apr 12. J Med Chem. 2024. PMID: 38607318

5

A promising chemical series of positive allosteric modulators of the μ-opioid receptor that enhance the antinociceptive efficacy of opioids but not their adverse effects.

Pryce KD, Kang HJ, Sakloth F, Liu Y, Khan S, Toth K, Kapoor A, Nicolais A, Che T, Qin L, Bertherat F, Kaniskan HÜ, Jin J, Cameron MD, Roth BL, Zachariou V, Filizola M. Pryce KD, et al. Among authors: qin l. Neuropharmacology. 2021 Sep 1;195:108673. doi: 10.1016/j.neuropharm.2021.108673. Epub 2021 Jun 18. Neuropharmacology. 2021. PMID: 34153316 Free PMC article.

6

Targeted Degradation of PRC1 Components, BMI1 and RING1B, via a Novel Protein Complex Degrader Strategy.

Park KS, Qin L, Kabir M, Luo K, Dale B, Zhong Y, Kim A, Wang GG, Kaniskan HÜ, Jin J. Park KS, et al. Among authors: qin l. Adv Sci (Weinh). 2023 Apr;10(10):e2205573. doi: 10.1002/advs.202205573. Epub 2023 Feb 3. Adv Sci (Weinh). 2023. PMID: 36737841 Free PMC article.

7

Ultra-High Proportion of Grain Boundaries in Zinc Metal Anode Spontaneously Inhibiting Dendrites Growth.

Lian S, Cai Z, Yan M, Sun C, Chai N, Zhang B, Yu K, Xu M, Zhu J, Pan X, Dai Y, Huang J, Mai B, Qin L, Shi W, Xin Q, Chen X, Fu K, An Q, Yu Q, Zhou L, Luo W, Zhao K, Wang X, Mai L. Lian S, et al. Among authors: qin l. Angew Chem Int Ed Engl. 2024 May 23:e202406292. doi: 10.1002/anie.202406292. Online ahead of print. Angew Chem Int Ed Engl. 2024. PMID: 38780997

8

Direct abdominal vein thrombus imaging (DATI): a contrast-free black-blood MR technique for the diagnosis of abdominal vein thrombosis.

Liao L, Chen J, Liu Z, Liang S, Qin L, Lin X, Pan S, Tan M, Huang L, Ruan Q, Huang Z, Shi C, Xie G. Liao L, et al. Among authors: qin l. Abdom Radiol (NY). 2024 May 23. doi: 10.1007/s00261-024-04335-3. Online ahead of print. Abdom Radiol (NY). 2024. PMID: 38780634

9

Physiological response of chestnuts (Castanea mollissima Blume) infected by pathogenic fungi and their correlation with fruit decay.

Wen A, Zhu Y, Geng Y, Qin L. Wen A, et al. Among authors: qin l. Food Chem X. 2024 May 7;22:101450. doi: 10.1016/j.fochx.2024.101450. eCollection 2024 Jun 30. Food Chem X. 2024. PMID: 38779498 Free PMC article.

10

Deep Batch Integration and Denoise of Single-Cell RNA-Seq Data.

Qin L, Zhang G, Zhang S, Chen Y. Qin L, et al. Adv Sci (Weinh). 2024 May 22:e2308934. doi: 10.1002/advs.202308934. Online ahead of print. Adv Sci (Weinh). 2024. PMID: 38778573

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