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Modulating Pathogenesis with Mobile-CRISPRi.
Qu J, Prasad NK, Yu MA, Chen S, Lyden A, Herrera N, Silvis MR, Crawford E, Looney MR, Peters JM, Rosenberg OS. Qu J, et al. Among authors: rosenberg os. J Bacteriol. 2019 Oct 21;201(22):e00304-19. doi: 10.1128/JB.00304-19. Print 2019 Nov 15. J Bacteriol. 2019. PMID: 31481541 Free PMC article.
Detection of Bacteria-Specific Metabolism Using Hyperpolarized [2-13C]Pyruvate.
Sriram R, Sun J, Villanueva-Meyer J, Mutch C, De Los Santos J, Peters J, Korenchan DE, Neumann K, Van Criekinge M, Kurhanewicz J, Rosenberg O, Wilson D, Ohliger MA. Sriram R, et al. ACS Infect Dis. 2018 May 11;4(5):797-805. doi: 10.1021/acsinfecdis.7b00234. Epub 2018 Feb 13. ACS Infect Dis. 2018. PMID: 29405697 Free PMC article.
Enabling genetic analysis of diverse bacteria with Mobile-CRISPRi.
Peters JM, Koo BM, Patino R, Heussler GE, Hearne CC, Qu J, Inclan YF, Hawkins JS, Lu CHS, Silvis MR, Harden MM, Osadnik H, Peters JE, Engel JN, Dutton RJ, Grossman AD, Gross CA, Rosenberg OS. Peters JM, et al. Among authors: rosenberg os. Nat Microbiol. 2019 Feb;4(2):244-250. doi: 10.1038/s41564-018-0327-z. Epub 2019 Jan 7. Nat Microbiol. 2019. PMID: 30617347 Free PMC article.
Controlling CRISPR-Cas9 with ligand-activated and ligand-deactivated sgRNAs.
Kundert K, Lucas JE, Watters KE, Fellmann C, Ng AH, Heineike BM, Fitzsimmons CM, Oakes BL, Qu J, Prasad N, Rosenberg OS, Savage DF, El-Samad H, Doudna JA, Kortemme T. Kundert K, et al. Among authors: rosenberg os. Nat Commun. 2019 May 9;10(1):2127. doi: 10.1038/s41467-019-09985-2. Nat Commun. 2019. PMID: 31073154 Free PMC article.
Sensing Living Bacteria in Vivo Using d-Alanine-Derived 11C Radiotracers.
Parker MFL, Luu JM, Schulte B, Huynh TL, Stewart MN, Sriram R, Yu MA, Jivan S, Turnbaugh PJ, Flavell RR, Rosenberg OS, Ohliger MA, Wilson DM. Parker MFL, et al. Among authors: rosenberg os. ACS Cent Sci. 2020 Feb 26;6(2):155-165. doi: 10.1021/acscentsci.9b00743. Epub 2020 Feb 4. ACS Cent Sci. 2020. PMID: 32123733 Free PMC article.
Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.
Gordon DE, Hiatt J, Bouhaddou M, Rezelj VV, Ulferts S, Braberg H, Jureka AS, Obernier K, Guo JZ, Batra J, Kaake RM, Weckstein AR, Owens TW, Gupta M, Pourmal S, Titus EW, Cakir M, Soucheray M, McGregor M, Cakir Z, Jang G, O'Meara MJ, Tummino TA, Zhang Z, Foussard H, Rojc A, Zhou Y, Kuchenov D, Hüttenhain R, Xu J, Eckhardt M, Swaney DL, Fabius JM, Ummadi M, Tutuncuoglu B, Rathore U, Modak M, Haas P, Haas KM, Naing ZZC, Pulido EH, Shi Y, Barrio-Hernandez I, Memon D, Petsalaki E, Dunham A, Marrero MC, Burke D, Koh C, Vallet T, Silvas JA, Azumaya CM, Billesbølle C, Brilot AF, Campbell MG, Diallo A, Dickinson MS, Diwanji D, Herrera N, Hoppe N, Kratochvil HT, Liu Y, Merz GE, Moritz M, Nguyen HC, Nowotny C, Puchades C, Rizo AN, Schulze-Gahmen U, Smith AM, Sun M, Young ID, Zhao J, Asarnow D, Biel J, Bowen A, Braxton JR, Chen J, Chio CM, Chio US, Deshpande I, Doan L, Faust B, Flores S, Jin M, Kim K, Lam VL, Li F, Li J, Li YL, Li Y, Liu X, Lo M, Lopez KE, Melo AA, Moss FR 3rd, Nguyen P, Paulino J, Pawar KI, Peters JK, Pospiech TH Jr, Safari M, Sangwan S, Schaefer K, Thomas PV, Thwin AC, Trenker R, Tse E, Tsui TKM, Wang F, Whitis N, Yu Z, Zhang K, Zhang Y, Zhou F, Saltzberg D; QCRG Structural… See abstract for full author list ➔ Gordon DE, et al. Among authors: rosenberg os. Science. 2020 Dec 4;370(6521):eabe9403. doi: 10.1126/science.abe9403. Epub 2020 Oct 15. Science. 2020. PMID: 33060197 Free PMC article.
Bi-paratopic and multivalent VH domains block ACE2 binding and neutralize SARS-CoV-2.
Bracken CJ, Lim SA, Solomon P, Rettko NJ, Nguyen DP, Zha BS, Schaefer K, Byrnes JR, Zhou J, Lui I, Liu J, Pance K; QCRG Structural Biology Consortium; Zhou XX, Leung KK, Wells JA. Bracken CJ, et al. Nat Chem Biol. 2021 Jan;17(1):113-121. doi: 10.1038/s41589-020-00679-1. Epub 2020 Oct 20. Nat Chem Biol. 2021. PMID: 33082574 Free PMC article.
50 results