Wiemer DF - Search Results

1

ω-Hydroxy isoprenoid bisphosphonates as linkable GGDPS inhibitors.

Bhuiyan NH, Varney ML, Bhattacharya DS, Payne WM, Mohs AM, Holstein SA, Wiemer DF. Bhuiyan NH, et al. Among authors: wiemer df. Bioorg Med Chem Lett. 2019 Oct 1;29(19):126633. doi: 10.1016/j.bmcl.2019.126633. Epub 2019 Aug 20. Bioorg Med Chem Lett. 2019. PMID: 31474482 Free PMC article.

2

Phosphonate and bisphosphonate analogues of farnesyl pyrophosphate as potential inhibitors of farnesyl protein transferase.

Holstein SA, Cermak DM, Wiemer DF, Lewis K, Hohl RJ. Holstein SA, et al. Among authors: wiemer df. Bioorg Med Chem. 1998 Jun;6(6):687-94. doi: 10.1016/s0968-0896(98)00034-0. Bioorg Med Chem. 1998. PMID: 9681134

3

2-(Acyloxy)ethylphosphonate analogues of prenyl pyrophosphates: synthesis and biological characterization.

Cermak DM, Wiemer DF, Lewis K, Hohl RJ. Cermak DM, et al. Among authors: wiemer df. Bioorg Med Chem. 2000 Dec;8(12):2729-37. doi: 10.1016/s0968-0896(00)00212-1. Bioorg Med Chem. 2000. PMID: 11131164

4

Isoprenoid pyrophosphate analogues regulate expression of Ras-related proteins.

Holstein SA, Wohlford-Lenane CL, Wiemer DF, Hohl RJ. Holstein SA, et al. Among authors: wiemer df. Biochemistry. 2003 Apr 22;42(15):4384-91. doi: 10.1021/bi027227m. Biochemistry. 2003. PMID: 12693933

5

Synthesis and activity of fluorescent isoprenoid pyrophosphate analogues.

Kim M, Kleckley TS, Wiemer AJ, Holstein SA, Hohl RJ, Wiemer DF. Kim M, et al. Among authors: wiemer aj, wiemer df. J Org Chem. 2004 Nov 26;69(24):8186-93. doi: 10.1021/jo049101w. J Org Chem. 2004. PMID: 15549786

6

Synthesis and structure-activity studies of schweinfurthin B analogs: Evidence for the importance of a D-ring hydrogen bond donor in expression of differential cytotoxicity.

Neighbors JD, Salnikova MS, Beutler JA, Wiemer DF. Neighbors JD, et al. Among authors: wiemer df. Bioorg Med Chem. 2006 Mar 15;14(6):1771-84. doi: 10.1016/j.bmc.2005.10.025. Epub 2005 Nov 14. Bioorg Med Chem. 2006. PMID: 16290161

7

Synthesis and biological activity of isoprenoid bisphosphonates.

Shull LW, Wiemer AJ, Hohl RJ, Wiemer DF. Shull LW, et al. Among authors: wiemer aj, wiemer df. Bioorg Med Chem. 2006 Jun 15;14(12):4130-6. doi: 10.1016/j.bmc.2006.02.010. Epub 2006 Mar 6. Bioorg Med Chem. 2006. PMID: 16517172

8

Total synthesis of (R,R,R)- and (S,S,S)-schweinfurthin F: differences of bioactivity in the enantiomeric series.

Mente NR, Wiemer AJ, Neighbors JD, Beutler JA, Hohl RJ, Wiemer DF. Mente NR, et al. Among authors: wiemer aj, wiemer df. Bioorg Med Chem Lett. 2007 Feb 15;17(4):911-5. doi: 10.1016/j.bmcl.2006.11.096. Epub 2006 Dec 12. Bioorg Med Chem Lett. 2007. PMID: 17236766

9

Synthesis of fluorescently tagged isoprenoid bisphosphonates that inhibit protein geranylgeranylation.

Maalouf MA, Wiemer AJ, Kuder CH, Hohl RJ, Wiemer DF. Maalouf MA, et al. Among authors: wiemer aj, wiemer df. Bioorg Med Chem. 2007 Mar 1;15(5):1959-66. doi: 10.1016/j.bmc.2007.01.002. Epub 2007 Jan 4. Bioorg Med Chem. 2007. PMID: 17254791

10

Mono- and dialkyl isoprenoid bisphosphonates as geranylgeranyl diphosphate synthase inhibitors.

Wiemer AJ, Yu JS, Lamb KM, Hohl RJ, Wiemer DF. Wiemer AJ, et al. Among authors: wiemer df. Bioorg Med Chem. 2008 Jan 1;16(1):390-9. doi: 10.1016/j.bmc.2007.09.029. Epub 2007 Sep 18. Bioorg Med Chem. 2008. PMID: 17905588

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