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Synthesis and highly potent anti-inflammatory activity of licofelone- and ketorolac-based 1-arylpyrrolizin-3-ones.
Madrigal DA, Escalante CH, Gutiérrez-Rebolledo GA, Cristobal-Luna JM, Gómez-García O, Hernández-Benitez RI, Esquivel-Campos AL, Pérez-Gutiérrez S, Chamorro-Cevallos GA, Delgado F, Tamariz J. Madrigal DA, et al. Among authors: hernandez benitez ri. Bioorg Med Chem. 2019 Oct 15;27(20):115053. doi: 10.1016/j.bmc.2019.115053. Epub 2019 Aug 20. Bioorg Med Chem. 2019. PMID: 31471100
Divergent Pd-catalyzed Functionalization of 4-Oxazolin-2-ones and 4-Methylene-2-oxazolidinones and Synthesis of Heterocyclic-Fused Indoles.
Yescas-Galicia D, Restrepo-Osorio RA, García-González AN, Hernández-Benítez RI, Espinoza-Hicks JC, Escalante CH, Barrera E, Santoyo BM, Delgado F, Tamariz J. Yescas-Galicia D, et al. Among authors: hernandez benitez ri. J Org Chem. 2022 Oct 7;87(19):13034-13052. doi: 10.1021/acs.joc.2c01563. Epub 2022 Sep 26. J Org Chem. 2022. PMID: 36153994
Enantiopure 4-oxazolin-2-ones and 4-methylene-2-oxazolidinones as chiral building blocks in a divergent asymmetric synthesis of heterocycles.
Santoyo BM, González-Romero C, Zárate-Zárate D, Hernández-Benitez RI, Pelayo V, Barrera E, Escalante CH, Fuentes-Benites A, Martínez-Morales G, López J, Vázquez MA, Delgado F, Jiménez-Vázquez HA, Tamariz J. Santoyo BM, et al. Among authors: hernandez benitez ri. Chirality. 2019 Sep;31(9):719-749. doi: 10.1002/chir.23109. Epub 2019 Jul 18. Chirality. 2019. PMID: 31318100