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Enhanced mTOR complex 1 signaling attenuates diabetic cardiac injury in OVE26 mice.
Xu X, Kobayashi S, Timm D, Huang Y, Zhao F, Shou W, Liang Q. Xu X, et al. Among authors: huang y. FASEB J. 2019 Nov;33(11):12800-12811. doi: 10.1096/fj.201901206R. Epub 2019 Aug 30. FASEB J. 2019. PMID: 31469601
These findings demonstrated that the enhanced mTORC1 signaling in the OVE26 diabetic heart was an adaptive response that limited cardiac dysfunction, suggesting that manipulations that enhance mTORC1 activity may reduce diabetic cardiac injury, in sharp contrast to the results pr …
These findings demonstrated that the enhanced mTORC1 signaling in the OVE26 diabetic heart was an adaptive response that limited cardiac dys …
Regulation of Akt/PKB activity by P21-activated kinase in cardiomyocytes.
Mao K, Kobayashi S, Jaffer ZM, Huang Y, Volden P, Chernoff J, Liang Q. Mao K, et al. Among authors: huang y. J Mol Cell Cardiol. 2008 Feb;44(2):429-34. doi: 10.1016/j.yjmcc.2007.10.016. Epub 2007 Dec 3. J Mol Cell Cardiol. 2008. PMID: 18054038 Free PMC article.
Diminished autophagy limits cardiac injury in mouse models of type 1 diabetes.
Xu X, Kobayashi S, Chen K, Timm D, Volden P, Huang Y, Gulick J, Yue Z, Robbins J, Epstein PN, Liang Q. Xu X, et al. Among authors: huang y. J Biol Chem. 2013 Jun 21;288(25):18077-92. doi: 10.1074/jbc.M113.474650. Epub 2013 May 8. J Biol Chem. 2013. PMID: 23658055 Free PMC article.
Doxorubicin-induced cardiomyocyte death is mediated by unchecked mitochondrial fission and mitophagy.
Catanzaro MP, Weiner A, Kaminaris A, Li C, Cai F, Zhao F, Kobayashi S, Kobayashi T, Huang Y, Sesaki H, Liang Q. Catanzaro MP, et al. Among authors: huang y. FASEB J. 2019 Oct;33(10):11096-11108. doi: 10.1096/fj.201802663R. Epub 2019 Jul 10. FASEB J. 2019. PMID: 31291545 Free PMC article.
., Kaminaris, A., Li, C., Cai, F., Zhao, F., Kobayashi, S., Kobayashi, T., Huang, Y., Sesaki, H., Liang, Q. Doxorubicin-induced cardiomyocyte death is mediated by unchecked mitochondrial fission and mitophagy....
., Kaminaris, A., Li, C., Cai, F., Zhao, F., Kobayashi, S., Kobayashi, T., Huang, Y., Sesaki, H., Liang, Q. Doxorubicin-induce …
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