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Paracetamol-Galactose Conjugate: A Novel Prodrug for an Old Analgesic Drug.
Sodano F, Lazzarato L, Rolando B, Spyrakis F, De Caro C, Magliocca S, Marabello D, Chegaev K, Gazzano E, Riganti C, Calignano A, Russo R, Rimoli MG. Sodano F, et al. Among authors: spyrakis f. Mol Pharm. 2019 Oct 7;16(10):4181-4189. doi: 10.1021/acs.molpharmaceut.9b00508. Epub 2019 Sep 12. Mol Pharm. 2019. PMID: 31465230 Free article.
PROTAC-Induced Glycogen Synthase Kinase 3β Degradation as a Potential Therapeutic Strategy for Alzheimer's Disease.
Guardigni M, Pruccoli L, Santini A, Simone A, Bersani M, Spyrakis F, Frabetti F, Uliassi E, Andrisano V, Pagliarani B, Fernández-Gómez P, Palomo V, Bolognesi ML, Tarozzi A, Milelli A. Guardigni M, et al. Among authors: spyrakis f. ACS Chem Neurosci. 2023 Jun 7;14(11):1963-1970. doi: 10.1021/acschemneuro.3c00096. Epub 2023 May 23. ACS Chem Neurosci. 2023. PMID: 37218653 Free PMC article.
Strigolactones as Broad-Spectrum Antivirals against β-Coronaviruses through Targeting the Main Protease Mpro.
Biolatti M, Blangetti M, Baggieri M, Marchi A, Gioacchini S, Bajetto G, Arnodo D, Bucci P, Fioravanti R, Kojouri M, Bersani M, D'Arrigo G, Siragusa L, Ghinato S, De Andrea M, Gugliesi F, Albano C, Pasquero S, Visentin I, D'Ugo E, Esposito F, Malune P, Tramontano E, Prandi C, Spyrakis F, Magurano F, Dell'Oste V. Biolatti M, et al. Among authors: spyrakis f. ACS Infect Dis. 2023 Jul 14;9(7):1310-1318. doi: 10.1021/acsinfecdis.3c00219. Epub 2023 Jun 26. ACS Infect Dis. 2023. PMID: 37358826
Tuning the Hydrophobicity of a Mitochondria-Targeted NO Photodonor.
Sodano F, Rolando B, Spyrakis F, Failla M, Lazzarato L, Gazzano E, Riganti C, Fruttero R, Gasco A, Sortino S. Sodano F, et al. Among authors: spyrakis f. ChemMedChem. 2018 Jun 20;13(12):1238-1245. doi: 10.1002/cmdc.201800088. Epub 2018 May 8. ChemMedChem. 2018. PMID: 29633541
Fluorescent Nitric Oxide Photodonors Based on BODIPY and Rhodamine Antennae.
Parisi C, Failla M, Fraix A, Rolando B, Gianquinto E, Spyrakis F, Gazzano E, Riganti C, Lazzarato L, Fruttero R, Gasco A, Sortino S. Parisi C, et al. Among authors: spyrakis f. Chemistry. 2019 Aug 22;25(47):11080-11084. doi: 10.1002/chem.201902062. Epub 2019 Jul 4. Chemistry. 2019. PMID: 31074543
DNA-Targeted NO Release Photoregulated by Green Light.
Parisi C, Fraix A, Guglielmo S, Spyrakis F, Rolando B, Lazzarato L, Fruttero R, Gasco A, Sortino S. Parisi C, et al. Among authors: spyrakis f. Chemistry. 2020 Oct 27;26(60):13627-13633. doi: 10.1002/chem.202001538. Epub 2020 Sep 28. Chemistry. 2020. PMID: 32453464
A generator of peroxynitrite activatable with red light.
Parisi C, Failla M, Fraix A, Menilli L, Moret F, Reddi E, Rolando B, Spyrakis F, Lazzarato L, Fruttero R, Gasco A, Sortino S. Parisi C, et al. Among authors: spyrakis f. Chem Sci. 2021 Mar 4;12(13):4740-4746. doi: 10.1039/d0sc06970a. Chem Sci. 2021. PMID: 34163730 Free PMC article.
Cryo-EM structures of staphylococcal IsdB bound to human hemoglobin reveal the process of heme extraction.
De Bei O, Marchetti M, Ronda L, Gianquinto E, Lazzarato L, Chirgadze DY, Hardwick SW, Cooper LR, Spyrakis F, Luisi BF, Campanini B, Bettati S. De Bei O, et al. Among authors: spyrakis f. Proc Natl Acad Sci U S A. 2022 Apr 5;119(14):e2116708119. doi: 10.1073/pnas.2116708119. Epub 2022 Mar 31. Proc Natl Acad Sci U S A. 2022. PMID: 35357971 Free PMC article.
114 results