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Tumor-derived CK1α mutations enhance MDMX inhibition of p53.
Liu X, Huang Q, Chen L, Zhang H, Schonbrunn E, Chen J. Liu X, et al. Among authors: schonbrunn e. Oncogene. 2020 Jan;39(1):176-186. doi: 10.1038/s41388-019-0979-z. Epub 2019 Aug 28. Oncogene. 2020. PMID: 31462704 Free PMC article.
Autoinhibition of MDMX by intramolecular p53 mimicry.
Chen L, Borcherds W, Wu S, Becker A, Schonbrunn E, Daughdrill GW, Chen J. Chen L, et al. Among authors: schonbrunn e. Proc Natl Acad Sci U S A. 2015 Apr 14;112(15):4624-9. doi: 10.1073/pnas.1420833112. Epub 2015 Mar 30. Proc Natl Acad Sci U S A. 2015. PMID: 25825738 Free PMC article.
The Akt activation inhibitor TCN-P inhibits Akt phosphorylation by binding to the PH domain of Akt and blocking its recruitment to the plasma membrane.
Berndt N, Yang H, Trinczek B, Betzi S, Zhang Z, Wu B, Lawrence NJ, Pellecchia M, Schönbrunn E, Cheng JQ, Sebti SM. Berndt N, et al. Among authors: schonbrunn e. Cell Death Differ. 2010 Nov;17(11):1795-804. doi: 10.1038/cdd.2010.63. Epub 2010 May 21. Cell Death Differ. 2010. PMID: 20489726 Free PMC article.
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