Williams IS - Search Results

1

Nonantioxidant Tetramethoxystilbene Abrogates α-Synuclein-Induced Yeast Cell Death but Not That Triggered by the Bax or βA4 Peptide.

Derf A, Mudududdla R, Akintade D, Williams IS, Abdullaha M, Chaudhuri B, Bharate SB. Derf A, et al. Among authors: williams is. ACS Omega. 2018 Aug 20;3(8):9513-9532. doi: 10.1021/acsomega.8b01154. eCollection 2018 Aug 31. ACS Omega. 2018. PMID: 31459084 Free PMC article.

2

Khellinoflavanone, a Semisynthetic Derivative of Khellin, Overcomes Benzo[a]pyrene Toxicity in Human Normal and Cancer Cells That Express CYP1A1.

Sharma R, Williams IS, Gatchie L, Sonawane VR, Chaudhuri B, Bharate SB. Sharma R, et al. Among authors: williams is. ACS Omega. 2018 Aug 1;3(8):8553-8566. doi: 10.1021/acsomega.8b01088. eCollection 2018 Aug 31. ACS Omega. 2018. PMID: 31458985 Free PMC article.

3

Biotransformation, Using Recombinant CYP450-Expressing Baker's Yeast Cells, Identifies a Novel CYP2D6.10^A122V Variant Which Is a Superior Metabolizer of Codeine to Morphine Than the Wild-Type Enzyme.

Williams IS, Gatchie L, Bharate SB, Chaudhuri B. Williams IS, et al. ACS Omega. 2018 Aug 9;3(8):8903-8912. doi: 10.1021/acsomega.8b00809. eCollection 2018 Aug 31. ACS Omega. 2018. PMID: 31459022 Free PMC article.

4

Synthesis and biological evaluation of pyrrole-based chalcones as CYP1 enzyme inhibitors, for possible prevention of cancer and overcoming cisplatin resistance.

Williams IS, Joshi P, Gatchie L, Sharma M, Satti NK, Vishwakarma RA, Chaudhuri B, Bharate SB. Williams IS, et al. Bioorg Med Chem Lett. 2017 Aug 15;27(16):3683-3687. doi: 10.1016/j.bmcl.2017.07.010. Epub 2017 Jul 4. Bioorg Med Chem Lett. 2017. PMID: 28711350 Free article.

5

Biotransformation of Chrysin to Baicalein: Selective C6-Hydroxylation of 5,7-Dihydroxyflavone Using Whole Yeast Cells Stably Expressing Human CYP1A1 Enzyme.

Williams IS, Chib S, Nuthakki VK, Gatchie L, Joshi P, Narkhede NA, Vishwakarma RA, Bharate SB, Saran S, Chaudhuri B. Williams IS, et al. J Agric Food Chem. 2017 Aug 30;65(34):7440-7446. doi: 10.1021/acs.jafc.7b02690. Epub 2017 Aug 15. J Agric Food Chem. 2017. PMID: 28782952

6

(E)-3-(3,4,5-Trimethoxyphenyl)-1-(pyridin-4-yl)prop-2-en-1-one, a heterocyclic chalcone is a potent and selective CYP1A1 inhibitor and cancer chemopreventive agent.

Horley NJ, Beresford KJM, Kaduskar S, Joshi P, McCann GJP, Ruparelia KC, Williams IS, Gatchie L, Sonawane VR, Bharate SB, Chaudhuri B. Horley NJ, et al. Among authors: williams is. Bioorg Med Chem Lett. 2017 Dec 15;27(24):5409-5414. doi: 10.1016/j.bmcl.2017.11.009. Epub 2017 Nov 6. Bioorg Med Chem Lett. 2017. PMID: 29138024

7

Glycyrrhiza glabra extract and quercetin reverses cisplatin resistance in triple-negative MDA-MB-468 breast cancer cells via inhibition of cytochrome P450 1B1 enzyme.

Sharma R, Gatchie L, Williams IS, Jain SK, Vishwakarma RA, Chaudhuri B, Bharate SB. Sharma R, et al. Among authors: williams is. Bioorg Med Chem Lett. 2017 Dec 15;27(24):5400-5403. doi: 10.1016/j.bmcl.2017.11.013. Epub 2017 Nov 7. Bioorg Med Chem Lett. 2017. PMID: 29150398

8

Identification of karanjin isolated from the Indian beech tree as a potent CYP1 enzyme inhibitor with cellular efficacy via screening of a natural product repository.

Joshi P, Sonawane VR, Williams IS, McCann GJP, Gatchie L, Sharma R, Satti N, Chaudhuri B, Bharate SB. Joshi P, et al. Among authors: williams is. Medchemcomm. 2018 Jan 8;9(2):371-382. doi: 10.1039/c7md00388a. eCollection 2018 Feb 1. Medchemcomm. 2018. PMID: 30108931 Free PMC article.

9

Furanoflavones pongapin and lanceolatin B blocks the cell cycle and induce senescence in CYP1A1-overexpressing breast cancer cells.

Sharma R, Williams IS, Gatchie L, Sonawane VR, Chaudhuri B, Bharate SB. Sharma R, et al. Among authors: williams is. Bioorg Med Chem. 2018 Dec 15;26(23-24):6076-6086. doi: 10.1016/j.bmc.2018.11.013. Epub 2018 Nov 10. Bioorg Med Chem. 2018. PMID: 30448188

10

CYP enzymes, expressed within live human suspension cells, are superior to widely-used microsomal enzymes in identifying potent CYP1A1/CYP1B1 inhibitors: Identification of quinazolinones as CYP1A1/CYP1B1 inhibitors that efficiently reverse B[a]P toxicity and cisplatin resistance.

Sonawane VR, Siddique MUM, Gatchie L, Williams IS, Bharate SB, Jayaprakash V, Sinha BN, Chaudhuri B. Sonawane VR, et al. Among authors: williams is. Eur J Pharm Sci. 2019 Apr 1;131:177-194. doi: 10.1016/j.ejps.2019.02.016. Epub 2019 Feb 15. Eur J Pharm Sci. 2019. PMID: 30776468

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

31 results

Search Page