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MTCH2 promotes adipogenesis in intramuscular preadipocytes via an m6A-YTHDF1-dependent mechanism.
Jiang Q, Sun B, Liu Q, Cai M, Wu R, Wang F, Yao Y, Wang Y, Wang X. Jiang Q, et al. Among authors: liu q. FASEB J. 2019 Feb;33(2):2971-2981. doi: 10.1096/fj.201801393RRR. Epub 2018 Oct 19. FASEB J. 2019. PMID: 30339471 Free PMC article.
This study provides comprehensive m(6)A profiles of LDM transcriptomes in pigs and suggests an essential role for m(6)A modification of MTCH2 in intramuscular fat regulation.-Jiang, Q., Sun, B., Liu, Q., Cai, M., Wu, R., Wang, F., Yao, Y., Wang, Y., Wang, X. …
This study provides comprehensive m(6)A profiles of LDM transcriptomes in pigs and suggests an essential role for m(6)A modification of MTCH …
METTL3 inhibits BMSC adipogenic differentiation by targeting the JAK1/STAT5/C/EBPβ pathway via an m6A-YTHDF2-dependent manner.
Yao Y, Bi Z, Wu R, Zhao Y, Liu Y, Liu Q, Wang Y, Wang X. Yao Y, et al. Among authors: liu y, liu q. FASEB J. 2019 Jun;33(6):7529-7544. doi: 10.1096/fj.201802644R. Epub 2019 Mar 13. FASEB J. 2019. PMID: 30865855
Our findings provide novel insights into the underlying molecular mechanisms of m(6)A modification in the regulation of BMSCs differentiating into adipocytes, which may pave a way to develop more effective therapeutic strategies in stem cell regenerative medicine and the treatmen …
Our findings provide novel insights into the underlying molecular mechanisms of m(6)A modification in the regulation of BMSCs differentiatin …
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